5fi8
From Proteopedia
(Difference between revisions)
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==Crystal structure of plasmodium falciparum dihydroorotate dehydrogenase bounded with DSM422 (Tetrahydro-2-naphthyl and 2-indanyl triazolopyrimidine)== | ==Crystal structure of plasmodium falciparum dihydroorotate dehydrogenase bounded with DSM422 (Tetrahydro-2-naphthyl and 2-indanyl triazolopyrimidine)== | ||
| - | <StructureSection load='5fi8' size='340' side='right' caption='[[5fi8]], [[Resolution|resolution]] 2.32Å' scene=''> | + | <StructureSection load='5fi8' size='340' side='right'caption='[[5fi8]], [[Resolution|resolution]] 2.32Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5fi8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FI8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FI8 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5fi8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plaf7 Plaf7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FI8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FI8 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5Y5:2-[1,1-BIS(FLUORANYL)ETHYL]-~{N}-[(2~{S})-7-BROMANYL-1,2,3,4-TETRAHYDRONAPHTHALEN-2-YL]-5-METHYL-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-AMINE'>5Y5</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=ORO:OROTIC+ACID'>ORO</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5Y5:2-[1,1-BIS(FLUORANYL)ETHYL]-~{N}-[(2~{S})-7-BROMANYL-1,2,3,4-TETRAHYDRONAPHTHALEN-2-YL]-5-METHYL-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-AMINE'>5Y5</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=ORO:OROTIC+ACID'>ORO</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PFF0160c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 PLAF7])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_dehydrogenase_(quinone) Dihydroorotate dehydrogenase (quinone)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.5.2 1.3.5.2] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_dehydrogenase_(quinone) Dihydroorotate dehydrogenase (quinone)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.5.2 1.3.5.2] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fi8 OCA], [http://pdbe.org/5fi8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fi8 RCSB], [http://www.ebi.ac.uk/pdbsum/5fi8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fi8 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fi8 OCA], [http://pdbe.org/5fi8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fi8 RCSB], [http://www.ebi.ac.uk/pdbsum/5fi8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fi8 ProSAT]</span></td></tr> | ||
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==See Also== | ==See Also== | ||
| - | *[[Dihydroorotate dehydrogenase|Dihydroorotate dehydrogenase]] | + | *[[Dihydroorotate dehydrogenase 3D structures|Dihydroorotate dehydrogenase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Plaf7]] | ||
[[Category: Deng, X]] | [[Category: Deng, X]] | ||
[[Category: Kokkonda, S]] | [[Category: Kokkonda, S]] | ||
Revision as of 16:10, 11 December 2019
Crystal structure of plasmodium falciparum dihydroorotate dehydrogenase bounded with DSM422 (Tetrahydro-2-naphthyl and 2-indanyl triazolopyrimidine)
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