This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5lzx
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | + | ||
==Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a UGA stop codon.== | ==Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a UGA stop codon.== | ||
| - | <StructureSection load='5lzx' size='340' side='right' caption='[[5lzx]], [[Resolution|resolution]] 3.67Å' scene=''> | + | <StructureSection load='5lzx' size='340' side='right'caption='[[5lzx]], [[Resolution|resolution]] 3.67Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5lzx]] is a 87 chain structure with sequence from [http://en.wikipedia.org/wiki/European_rabbit European rabbit] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LZX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LZX FirstGlance]. <br> | <table><tr><td colspan='2'>[[5lzx]] is a 87 chain structure with sequence from [http://en.wikipedia.org/wiki/European_rabbit European rabbit] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LZX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LZX FirstGlance]. <br> | ||
| Line 8: | Line 8: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lzx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lzx OCA], [http://pdbe.org/5lzx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lzx RCSB], [http://www.ebi.ac.uk/pdbsum/5lzx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lzx ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lzx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lzx OCA], [http://pdbe.org/5lzx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lzx RCSB], [http://www.ebi.ac.uk/pdbsum/5lzx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lzx ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | {{Large structure}} | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/U3KPD5_RABIT U3KPD5_RABIT]] Binds to the 23S rRNA.[RuleBase:RU000576] [[http://www.uniprot.org/uniprot/PELO_HUMAN PELO_HUMAN]] Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity (Potential). [[http://www.uniprot.org/uniprot/G1SS70_RABIT G1SS70_RABIT]] May play a role during erythropoiesis through regulation of transcription factor DDIT3.[HAMAP-Rule:MF_03122] | [[http://www.uniprot.org/uniprot/U3KPD5_RABIT U3KPD5_RABIT]] Binds to the 23S rRNA.[RuleBase:RU000576] [[http://www.uniprot.org/uniprot/PELO_HUMAN PELO_HUMAN]] Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity (Potential). [[http://www.uniprot.org/uniprot/G1SS70_RABIT G1SS70_RABIT]] May play a role during erythropoiesis through regulation of transcription factor DDIT3.[HAMAP-Rule:MF_03122] | ||
| Line 28: | Line 27: | ||
</StructureSection> | </StructureSection> | ||
[[Category: European rabbit]] | [[Category: European rabbit]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Oryctolagus cuniculus]] | [[Category: Oryctolagus cuniculus]] | ||
[[Category: Brown, A]] | [[Category: Brown, A]] | ||
Revision as of 16:38, 11 December 2019
Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a UGA stop codon.
| |||||||||||
