5lzx
From Proteopedia
(Difference between revisions)
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==Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a UGA stop codon.== | ==Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a UGA stop codon.== | ||
| - | <StructureSection load='5lzx' size='340' side='right' caption='[[5lzx]], [[Resolution|resolution]] 3.67Å' scene=''> | + | <StructureSection load='5lzx' size='340' side='right'caption='[[5lzx]], [[Resolution|resolution]] 3.67Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5lzx]] is a 87 chain structure with sequence from [http://en.wikipedia.org/wiki/European_rabbit European rabbit] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LZX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LZX FirstGlance]. <br> | <table><tr><td colspan='2'>[[5lzx]] is a 87 chain structure with sequence from [http://en.wikipedia.org/wiki/European_rabbit European rabbit] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LZX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LZX FirstGlance]. <br> | ||
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lzx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lzx OCA], [http://pdbe.org/5lzx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lzx RCSB], [http://www.ebi.ac.uk/pdbsum/5lzx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lzx ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lzx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lzx OCA], [http://pdbe.org/5lzx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lzx RCSB], [http://www.ebi.ac.uk/pdbsum/5lzx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lzx ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | {{Large structure}} | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/U3KPD5_RABIT U3KPD5_RABIT]] Binds to the 23S rRNA.[RuleBase:RU000576] [[http://www.uniprot.org/uniprot/PELO_HUMAN PELO_HUMAN]] Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity (Potential). [[http://www.uniprot.org/uniprot/G1SS70_RABIT G1SS70_RABIT]] May play a role during erythropoiesis through regulation of transcription factor DDIT3.[HAMAP-Rule:MF_03122] | [[http://www.uniprot.org/uniprot/U3KPD5_RABIT U3KPD5_RABIT]] Binds to the 23S rRNA.[RuleBase:RU000576] [[http://www.uniprot.org/uniprot/PELO_HUMAN PELO_HUMAN]] Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity (Potential). [[http://www.uniprot.org/uniprot/G1SS70_RABIT G1SS70_RABIT]] May play a role during erythropoiesis through regulation of transcription factor DDIT3.[HAMAP-Rule:MF_03122] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: European rabbit]] | [[Category: European rabbit]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Oryctolagus cuniculus]] | [[Category: Oryctolagus cuniculus]] | ||
[[Category: Brown, A]] | [[Category: Brown, A]] | ||
Revision as of 16:38, 11 December 2019
Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a UGA stop codon.
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