5uag
From Proteopedia
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==Escherichia coli RNA polymerase mutant - RpoB D516V== | ==Escherichia coli RNA polymerase mutant - RpoB D516V== | ||
| - | <StructureSection load='5uag' size='340' side='right' caption='[[5uag]], [[Resolution|resolution]] 3.40Å' scene=''> | + | <StructureSection load='5uag' size='340' side='right'caption='[[5uag]], [[Resolution|resolution]] 3.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5uag]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UAG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UAG FirstGlance]. <br> | <table><tr><td colspan='2'>[[5uag]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UAG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UAG FirstGlance]. <br> | ||
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uag OCA], [http://pdbe.org/5uag PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uag RCSB], [http://www.ebi.ac.uk/pdbsum/5uag PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uag ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uag OCA], [http://pdbe.org/5uag PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uag RCSB], [http://www.ebi.ac.uk/pdbsum/5uag PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uag ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | {{Large structure}} | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/RPOZ_ECOLI RPOZ_ECOLI]] Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.[HAMAP-Rule:MF_00366] [[http://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059] [[http://www.uniprot.org/uniprot/RPOC_ECOLI RPOC_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01322] [[http://www.uniprot.org/uniprot/RPOB_ECOLI RPOB_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01321] [[http://www.uniprot.org/uniprot/RPOD_ECOLI RPOD_ECOLI]] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This is the primary sigma factor of this bacterium. | [[http://www.uniprot.org/uniprot/RPOZ_ECOLI RPOZ_ECOLI]] Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.[HAMAP-Rule:MF_00366] [[http://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059] [[http://www.uniprot.org/uniprot/RPOC_ECOLI RPOC_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01322] [[http://www.uniprot.org/uniprot/RPOB_ECOLI RPOB_ECOLI]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01321] [[http://www.uniprot.org/uniprot/RPOD_ECOLI RPOD_ECOLI]] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This is the primary sigma factor of this bacterium. | ||
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</div> | </div> | ||
<div class="pdbe-citations 5uag" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5uag" style="background-color:#fffaf0;"></div> | ||
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| + | ==See Also== | ||
| + | *[[RNA polymerase|RNA polymerase]] | ||
| + | *[[Sigma factor|Sigma factor]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: DNA-directed RNA polymerase]] | [[Category: DNA-directed RNA polymerase]] | ||
[[Category: Ecoli]] | [[Category: Ecoli]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Garcia, G A]] | [[Category: Garcia, G A]] | ||
[[Category: Molodtsov, V]] | [[Category: Molodtsov, V]] | ||
Revision as of 17:04, 11 December 2019
Escherichia coli RNA polymerase mutant - RpoB D516V
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Categories: DNA-directed RNA polymerase | Ecoli | Large Structures | Garcia, G A | Molodtsov, V | Murakami, K S | Scharf, N T | Stefan, M A | Antibiotic | Inhibitor | Rifampin | Rifamycin | Rifamycin resistant mutation | Rna polymerase | Rpob-d516v | Transferase-transferase inhibitor complex | Tuberculosis
