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5wdw

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==Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 10k (SRI-30027)==
==Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 10k (SRI-30027)==
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<StructureSection load='5wdw' size='340' side='right' caption='[[5wdw]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='5wdw' size='340' side='right'caption='[[5wdw]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5wdw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WDW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WDW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5wdw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/I09a0 I09a0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WDW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WDW FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8KU:2-[(2S)-1-{[(2-chlorophenyl)sulfanyl]acetyl}pyrrolidin-2-yl]-N-{[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl}-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxamide'>8KU</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8KU:2-[(2S)-1-{[(2-chlorophenyl)sulfanyl]acetyl}pyrrolidin-2-yl]-N-{[(2S)-2,3-dihydro-1-benzofuran-2-yl]methyl}-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxamide'>8KU</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5w3i|5w3i]], [[5w44|5w44]], [[5w73|5w73]], [[5w7u|5w7u]], [[5w92|5w92]], [[5w9g|5w9g]], [[5wa6|5wa6]], [[5wa7|5wa7]], [[5wap|5wap]], [[5wb3|5wb3]], [[5wcs|5wcs]], [[5wct|5wct]], [[5wdn|5wdn]], [[5wdc|5wdc]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5w3i|5w3i]], [[5w44|5w44]], [[5w73|5w73]], [[5w7u|5w7u]], [[5w92|5w92]], [[5w9g|5w9g]], [[5wa6|5wa6]], [[5wa7|5wa7]], [[5wap|5wap]], [[5wb3|5wb3]], [[5wcs|5wcs]], [[5wct|5wct]], [[5wdn|5wdn]], [[5wdc|5wdc]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=641501 I09A0])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wdw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wdw OCA], [http://pdbe.org/5wdw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wdw RCSB], [http://www.ebi.ac.uk/pdbsum/5wdw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wdw ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wdw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wdw OCA], [http://pdbe.org/5wdw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wdw RCSB], [http://www.ebi.ac.uk/pdbsum/5wdw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wdw ProSAT]</span></td></tr>
</table>
</table>
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</div>
</div>
<div class="pdbe-citations 5wdw" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5wdw" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[RNA polymerase|RNA polymerase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: I09a0]]
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[[Category: Large Structures]]
[[Category: Kumar, G]]
[[Category: Kumar, G]]
[[Category: White, S W]]
[[Category: White, S W]]

Revision as of 17:34, 11 December 2019

Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 10k (SRI-30027)

PDB ID 5wdw

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