6lc1
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structural basis of NR4A1 bound to the human pituitary proopiomelanocortin gene promoter== | |
| - | + | <StructureSection load='6lc1' size='340' side='right'caption='[[6lc1]], [[Resolution|resolution]] 3.12Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6lc1]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LC1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6LC1 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6lc1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lc1 OCA], [http://pdbe.org/6lc1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6lc1 RCSB], [http://www.ebi.ac.uk/pdbsum/6lc1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6lc1 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN]] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Chen, Y]] | [[Category: Chen, Y]] | ||
[[Category: Jiang, L]] | [[Category: Jiang, L]] | ||
| + | [[Category: Dna binding protein]] | ||
| + | [[Category: Dna binding protein-dna complex]] | ||
| + | [[Category: Nuclear receptor]] | ||
Revision as of 07:42, 18 December 2019
Structural basis of NR4A1 bound to the human pituitary proopiomelanocortin gene promoter
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