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6ndo
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the dark-adapted full-length bacteriophytochrome XccBphP mutant L193N from Xanthomonas campestris== | |
| - | + | <StructureSection load='6ndo' size='340' side='right'caption='[[6ndo]], [[Resolution|resolution]] 3.58Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ndo]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NDO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NDO FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BLA:BILIVERDINE+IX+ALPHA'>BLA</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ndo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ndo OCA], [http://pdbe.org/6ndo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ndo RCSB], [http://www.ebi.ac.uk/pdbsum/6ndo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ndo ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BPHY_XANC8 BPHY_XANC8]] Photoreceptor which exists in two forms that are reversibly interconvertible by light: far-red light (733 nm) converts protein to the red-absorbing (Pr) form, while red light (630 nm) partly converts the protein to the far-red-absorbing (Pfr) form (PubMed:27107635). Regulates virulence of X.campestris pv. campestris on its host plants, perhaps by fine-tuning expression to ambient light levels and/or spatial cues (PubMed:27621284). The Pr form may sense light and partially inhibit virulence; in the dark (Pfr form) biofilm and xanathan production rise and bacteria are more virulent (PubMed:27621284). Strains overexpressing this protein have significantly decreased amounts of extracellular beta-1,4-endoglucanase, produce less xanthin and have decreased transcription of genes involved in virulence such as endoglucanases, type 2 secretion systems, xanthan production and flagellar-dependent motility (PubMed:27621284).<ref>PMID:27107635</ref> <ref>PMID:27621284</ref> <ref>PMID:27621284</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bonomi, H R]] | ||
| + | [[Category: Chavas, L]] | ||
| + | [[Category: Conforte, V]] | ||
| + | [[Category: Goldbaum, F A]] | ||
| + | [[Category: Klinke, S]] | ||
| + | [[Category: Malamud, F]] | ||
| + | [[Category: Otero, L H]] | ||
| + | [[Category: Rinaldi, J]] | ||
| + | [[Category: Sirigu, S]] | ||
| + | [[Category: Bacterial protein]] | ||
| + | [[Category: Photoreceptor]] | ||
| + | [[Category: Photosensor]] | ||
| + | [[Category: Phytochrome]] | ||
| + | [[Category: Phytopathogen]] | ||
| + | [[Category: Red/far-red light]] | ||
| + | [[Category: Signal transduction]] | ||
| + | [[Category: Signaling protein]] | ||
Revision as of 07:43, 18 December 2019
Crystal structure of the dark-adapted full-length bacteriophytochrome XccBphP mutant L193N from Xanthomonas campestris
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