This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5u1u
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist A740003== | ==Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist A740003== | ||
| - | <StructureSection load='5u1u' size='340' side='right' caption='[[5u1u]], [[Resolution|resolution]] 3.60Å' scene=''> | + | <StructureSection load='5u1u' size='340' side='right'caption='[[5u1u]], [[Resolution|resolution]] 3.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5u1u]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U1U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5U1U FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5u1u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ailme Ailme]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U1U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5U1U FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7S4:N-{(1R)-1-[N-CYANO-N-(QUINOLIN-5-YL)CARBAMIMIDAMIDO]-2,2-DIMETHYLPROPYL}-2-(3,4-DIMETHOXYPHENYL)ACETAMIDE'>7S4</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7S4:N-{(1R)-1-[N-CYANO-N-(QUINOLIN-5-YL)CARBAMIMIDAMIDO]-2,2-DIMETHYLPROPYL}-2-(3,4-DIMETHOXYPHENYL)ACETAMIDE'>7S4</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5u1l|5u1l]], [[5u1v|5u1v]], [[5u1w|5u1w]], [[5u1x|5u1x]], [[5u1y|5u1y]], [[5u2h|5u2h]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5u1l|5u1l]], [[5u1v|5u1v]], [[5u1w|5u1w]], [[5u1x|5u1x]], [[5u1y|5u1y]], [[5u2h|5u2h]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">P2RX7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9646 AILME])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5u1u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u1u OCA], [http://pdbe.org/5u1u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u1u RCSB], [http://www.ebi.ac.uk/pdbsum/5u1u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u1u ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5u1u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u1u OCA], [http://pdbe.org/5u1u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u1u RCSB], [http://www.ebi.ac.uk/pdbsum/5u1u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u1u ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| Line 23: | Line 24: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Ailme]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Karasawa, A]] | [[Category: Karasawa, A]] | ||
[[Category: Kawate, T]] | [[Category: Kawate, T]] | ||
[[Category: Membrane protein]] | [[Category: Membrane protein]] | ||
[[Category: Membrane protein: atp-gated ion channel: allosteric antagonist bound: closed state]] | [[Category: Membrane protein: atp-gated ion channel: allosteric antagonist bound: closed state]] | ||
Revision as of 09:04, 18 December 2019
Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist A740003
| |||||||||||
