5u1u
From Proteopedia
(Difference between revisions)
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==Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist A740003== | ==Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist A740003== | ||
| - | <StructureSection load='5u1u' size='340' side='right' caption='[[5u1u]], [[Resolution|resolution]] 3.60Å' scene=''> | + | <StructureSection load='5u1u' size='340' side='right'caption='[[5u1u]], [[Resolution|resolution]] 3.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5u1u]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U1U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5U1U FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5u1u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ailme Ailme]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U1U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5U1U FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7S4:N-{(1R)-1-[N-CYANO-N-(QUINOLIN-5-YL)CARBAMIMIDAMIDO]-2,2-DIMETHYLPROPYL}-2-(3,4-DIMETHOXYPHENYL)ACETAMIDE'>7S4</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7S4:N-{(1R)-1-[N-CYANO-N-(QUINOLIN-5-YL)CARBAMIMIDAMIDO]-2,2-DIMETHYLPROPYL}-2-(3,4-DIMETHOXYPHENYL)ACETAMIDE'>7S4</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5u1l|5u1l]], [[5u1v|5u1v]], [[5u1w|5u1w]], [[5u1x|5u1x]], [[5u1y|5u1y]], [[5u2h|5u2h]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5u1l|5u1l]], [[5u1v|5u1v]], [[5u1w|5u1w]], [[5u1x|5u1x]], [[5u1y|5u1y]], [[5u2h|5u2h]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">P2RX7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9646 AILME])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5u1u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u1u OCA], [http://pdbe.org/5u1u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u1u RCSB], [http://www.ebi.ac.uk/pdbsum/5u1u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u1u ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5u1u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u1u OCA], [http://pdbe.org/5u1u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u1u RCSB], [http://www.ebi.ac.uk/pdbsum/5u1u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u1u ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Ailme]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Karasawa, A]] | [[Category: Karasawa, A]] | ||
[[Category: Kawate, T]] | [[Category: Kawate, T]] | ||
[[Category: Membrane protein]] | [[Category: Membrane protein]] | ||
[[Category: Membrane protein: atp-gated ion channel: allosteric antagonist bound: closed state]] | [[Category: Membrane protein: atp-gated ion channel: allosteric antagonist bound: closed state]] | ||
Revision as of 09:04, 18 December 2019
Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist A740003
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