6d9j
From Proteopedia
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==Mammalian 80S ribosome with a double translocated CrPV-IRES, P-sitetRNA and eRF1.== | ==Mammalian 80S ribosome with a double translocated CrPV-IRES, P-sitetRNA and eRF1.== | ||
| - | <StructureSection load='6d9j' size='340' side='right' caption='[[6d9j]], [[Resolution|resolution]] 3.20Å' scene=''> | + | <StructureSection load='6d9j' size='340' side='right'caption='[[6d9j]], [[Resolution|resolution]] 3.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6d9j]] is a 85 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D9J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D9J FirstGlance]. <br> | <table><tr><td colspan='2'>[[6d9j]] is a 85 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D9J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D9J FirstGlance]. <br> | ||
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d9j OCA], [http://pdbe.org/6d9j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d9j RCSB], [http://www.ebi.ac.uk/pdbsum/6d9j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d9j ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d9j OCA], [http://pdbe.org/6d9j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d9j RCSB], [http://www.ebi.ac.uk/pdbsum/6d9j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d9j ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | {{Large structure}} | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/EF2_HUMAN EF2_HUMAN]] Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. [[http://www.uniprot.org/uniprot/U3KPD5_RABIT U3KPD5_RABIT]] Binds to the 23S rRNA.[RuleBase:RU000576] [[http://www.uniprot.org/uniprot/G1SS70_RABIT G1SS70_RABIT]] May play a role during erythropoiesis through regulation of transcription factor DDIT3.[HAMAP-Rule:MF_03122] | [[http://www.uniprot.org/uniprot/EF2_HUMAN EF2_HUMAN]] Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. [[http://www.uniprot.org/uniprot/U3KPD5_RABIT U3KPD5_RABIT]] Binds to the 23S rRNA.[RuleBase:RU000576] [[http://www.uniprot.org/uniprot/G1SS70_RABIT G1SS70_RABIT]] May play a role during erythropoiesis through regulation of transcription factor DDIT3.[HAMAP-Rule:MF_03122] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Oryctolagus cuniculus]] | [[Category: Oryctolagus cuniculus]] | ||
[[Category: Fernandez, I S]] | [[Category: Fernandez, I S]] | ||
Revision as of 10:01, 18 December 2019
Mammalian 80S ribosome with a double translocated CrPV-IRES, P-sitetRNA and eRF1.
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