6ncl

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{{Large structure}}
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==Near-atomic structure of icosahedrally averaged PBCV-1 capsid==
==Near-atomic structure of icosahedrally averaged PBCV-1 capsid==
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<StructureSection load='6ncl' size='340' side='right' caption='[[6ncl]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
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<StructureSection load='6ncl' size='340' side='right'caption='[[6ncl]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6ncl]] is a 115 chain structure with sequence from [http://en.wikipedia.org/wiki/Paramecium_bursaria_chlorella_virus_1 Paramecium bursaria chlorella virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NCL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NCL FirstGlance]. <br>
<table><tr><td colspan='2'>[[6ncl]] is a 115 chain structure with sequence from [http://en.wikipedia.org/wiki/Paramecium_bursaria_chlorella_virus_1 Paramecium bursaria chlorella virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NCL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NCL FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ncl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ncl OCA], [http://pdbe.org/6ncl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ncl RCSB], [http://www.ebi.ac.uk/pdbsum/6ncl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ncl ProSAT]</span></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ncl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ncl OCA], [http://pdbe.org/6ncl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ncl RCSB], [http://www.ebi.ac.uk/pdbsum/6ncl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ncl ProSAT]</span></td></tr>
</table>
</table>
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{{Large structure}}
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Although the nucleocytoplasmic large DNA viruses (NCLDVs) are one of the largest group of viruses that infect many eukaryotic hosts, the near-atomic resolution structures of these viruses have remained unknown. Here we describe a 3.5 A resolution icosahedrally averaged capsid structure of Paramecium bursaria chlorella virus 1 (PBCV-1). This structure consists of 5040 copies of the major capsid protein, 60 copies of the penton protein and 1800 minor capsid proteins of which there are 13 different types. The minor capsid proteins form a hexagonal network below the outer capsid shell, stabilizing the capsid by binding neighboring capsomers together. The size of the viral capsid is determined by a tape-measure, minor capsid protein of which there are 60 copies in the virion. Homologs of the tape-measure protein and some of the other minor capsid proteins exist in other NCLDVs. Thus, a similar capsid assembly pathway might be used by other NCLDVs.
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Near-atomic structure of a giant virus.,Fang Q, Zhu D, Agarkova I, Adhikari J, Klose T, Liu Y, Chen Z, Sun Y, Gross ML, Van Etten JL, Zhang X, Rossmann MG Nat Commun. 2019 Jan 23;10(1):388. doi: 10.1038/s41467-019-08319-6. PMID:30674888<ref>PMID:30674888</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 6ncl" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Paramecium bursaria chlorella virus 1]]
[[Category: Paramecium bursaria chlorella virus 1]]
[[Category: Fang, Q]]
[[Category: Fang, Q]]

Revision as of 11:26, 18 December 2019

Near-atomic structure of icosahedrally averaged PBCV-1 capsid

PDB ID 6ncl

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