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6u8b

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<StructureSection load='6u8b' size='340' side='right'caption='[[6u8b]], [[Resolution|resolution]] 1.26&Aring;' scene=''>
<StructureSection load='6u8b' size='340' side='right'caption='[[6u8b]], [[Resolution|resolution]] 1.26&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6u8b]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6U8B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6U8B FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6u8b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6U8B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6U8B FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=Q1M:3-{[(5-bromo-2-methoxyphenyl)sulfonyl]amino}-5-chloro-2-hydroxybenzoic+acid'>Q1M</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=Q1M:3-{[(5-bromo-2-methoxyphenyl)sulfonyl]amino}-5-chloro-2-hydroxybenzoic+acid'>Q1M</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">WDR5, BIG3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6u8b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6u8b OCA], [http://pdbe.org/6u8b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6u8b RCSB], [http://www.ebi.ac.uk/pdbsum/6u8b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6u8b ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6u8b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6u8b OCA], [http://pdbe.org/6u8b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6u8b RCSB], [http://www.ebi.ac.uk/pdbsum/6u8b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6u8b ProSAT]</span></td></tr>
</table>
</table>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Wang, F]]
[[Category: Wang, F]]

Revision as of 13:19, 18 December 2019

Discovery and optimization of salicyclic acid-derived sulfonamide inhibitors of the WDR5:MYC protein-protein interaction

PDB ID 6u8b

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