This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6pyf
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Sex Hormone-binding globulin mutant E176K in complex with Estradiol== | |
| - | + | <StructureSection load='6pyf' size='340' side='right'caption='[[6pyf]], [[Resolution|resolution]] 1.73Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6pyf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PYF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PYF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EST:ESTRADIOL'>EST</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pyf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pyf OCA], [http://pdbe.org/6pyf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pyf RCSB], [http://www.ebi.ac.uk/pdbsum/6pyf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pyf ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SHBG_HUMAN SHBG_HUMAN]] Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Das, S]] | ||
| + | [[Category: Petegem, F Van]] | ||
| + | [[Category: Round, P W]] | ||
| + | [[Category: Wu, T S]] | ||
| + | [[Category: Binding globulin]] | ||
| + | [[Category: Hormone]] | ||
| + | [[Category: Sex steroid]] | ||
| + | [[Category: Transport]] | ||
Revision as of 09:13, 25 December 2019
Sex Hormone-binding globulin mutant E176K in complex with Estradiol
| |||||||||||
