5dc5

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==Crystal structure of D176N HDAC8 in complex with M344==
==Crystal structure of D176N HDAC8 in complex with M344==
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<StructureSection load='5dc5' size='340' side='right' caption='[[5dc5]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
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<StructureSection load='5dc5' size='340' side='right'caption='[[5dc5]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5dc5]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DC5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DC5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5dc5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DC5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DC5 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B3N:4-(DIMETHYLAMINO)-N-[7-(HYDROXYAMINO)-7-OXOHEPTYL]BENZAMIDE'>B3N</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B3N:4-(DIMETHYLAMINO)-N-[7-(HYDROXYAMINO)-7-OXOHEPTYL]BENZAMIDE'>B3N</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dc6|5dc6]], [[5dc7|5dc7]], [[5dc8|5dc8]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dc6|5dc6]], [[5dc7|5dc7]], [[5dc8|5dc8]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HDAC8, HDACL1, CDA07 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_deacetylase Histone deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.98 3.5.1.98] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_deacetylase Histone deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.98 3.5.1.98] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dc5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dc5 OCA], [http://pdbe.org/5dc5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dc5 RCSB], [http://www.ebi.ac.uk/pdbsum/5dc5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dc5 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dc5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dc5 OCA], [http://pdbe.org/5dc5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dc5 RCSB], [http://www.ebi.ac.uk/pdbsum/5dc5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dc5 ProSAT]</span></td></tr>
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==See Also==
==See Also==
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*[[Histone deacetylase|Histone deacetylase]]
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*[[Histone deacetylase 3D structures|Histone deacetylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Histone deacetylase]]
[[Category: Histone deacetylase]]
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Christianson, D W]]
[[Category: Christianson, D W]]
[[Category: Decroos, C]]
[[Category: Decroos, C]]

Revision as of 11:20, 25 December 2019

Crystal structure of D176N HDAC8 in complex with M344

PDB ID 5dc5

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