5et3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==Crystal Structure of De novo Designed Fullerene organizing peptide==
==Crystal Structure of De novo Designed Fullerene organizing peptide==
-
<StructureSection load='5et3' size='340' side='right' caption='[[5et3]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
+
<StructureSection load='5et3' size='340' side='right'caption='[[5et3]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5et3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ET3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ET3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5et3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ET3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ET3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=60C:(C_{60}-I_{H})[5,6]FULLERENE'>60C</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=60C:(C_{60}-I_{H})[5,6]FULLERENE'>60C</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5et3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5et3 OCA], [http://pdbe.org/5et3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5et3 RCSB], [http://www.ebi.ac.uk/pdbsum/5et3 PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5et3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5et3 OCA], [http://pdbe.org/5et3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5et3 RCSB], [http://www.ebi.ac.uk/pdbsum/5et3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5et3 ProSAT]</span></td></tr>
</table>
</table>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Learning to engineer self-assembly would enable the precise organization of molecules by design to create matter with tailored properties. Here we demonstrate that proteins can direct the self-assembly of buckminsterfullerene (C60) into ordered superstructures. A previously engineered tetrameric helical bundle binds C60 in solution, rendering it water soluble. Two tetramers associate with one C60, promoting further organization revealed in a 1.67-A crystal structure. Fullerene groups occupy periodic lattice sites, sandwiched between two Tyr residues from adjacent tetramers. Strikingly, the assembly exhibits high charge conductance, whereas both the protein-alone crystal and amorphous C60 are electrically insulating. The affinity of C60 for its crystal-binding site is estimated to be in the nanomolar range, with lattices of known protein crystals geometrically compatible with incorporating the motif. Taken together, these findings suggest a new means of organizing fullerene molecules into a rich variety of lattices to generate new properties by design.
 +
 +
Protein-directed self-assembly of a fullerene crystal.,Kim KH, Ko DK, Kim YT, Kim NH, Paul J, Zhang SQ, Murray CB, Acharya R, DeGrado WF, Kim YH, Grigoryan G Nat Commun. 2016 Apr 26;7:11429. doi: 10.1038/ncomms11429. PMID:27113637<ref>PMID:27113637</ref>
 +
 +
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 +
</div>
 +
<div class="pdbe-citations 5et3" style="background-color:#fffaf0;"></div>
 +
== References ==
 +
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Acharya, R]]
[[Category: Acharya, R]]
[[Category: DeGrado, W F]]
[[Category: DeGrado, W F]]

Revision as of 11:35, 25 December 2019

Crystal Structure of De novo Designed Fullerene organizing peptide

PDB ID 5et3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5et3"
Personal tools