5hl1
From Proteopedia
(Difference between revisions)
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==Crystal structure of glutaminase C in complex with inhibitor CB-839== | ==Crystal structure of glutaminase C in complex with inhibitor CB-839== | ||
| - | <StructureSection load='5hl1' size='340' side='right' caption='[[5hl1]], [[Resolution|resolution]] 2.40Å' scene=''> | + | <StructureSection load='5hl1' size='340' side='right'caption='[[5hl1]], [[Resolution|resolution]] 2.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5hl1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HL1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HL1 FirstGlance]. <br> | <table><tr><td colspan='2'>[[5hl1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HL1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HL1 FirstGlance]. <br> | ||
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== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/GLSK_HUMAN GLSK_HUMAN]] Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. | [[http://www.uniprot.org/uniprot/GLSK_HUMAN GLSK_HUMAN]] Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. | ||
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| + | ==See Also== | ||
| + | *[[Glutaminase 3D structures|Glutaminase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Glutaminase]] | [[Category: Glutaminase]] | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Cerione, R A]] | [[Category: Cerione, R A]] | ||
[[Category: Huang, Q]] | [[Category: Huang, Q]] | ||
[[Category: Cb-839]] | [[Category: Cb-839]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
Revision as of 11:42, 25 December 2019
Crystal structure of glutaminase C in complex with inhibitor CB-839
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