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Beta-2 microglobulin
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<StructureSection load='' size='350' side='right' scene='45/459284/Cv/1' caption='Human β-2 microglobulin (green) complex with MHC I (magenta) and HCMV PP65 nonapeptide (cyan), [[3mrb]]'> | <StructureSection load='' size='350' side='right' scene='45/459284/Cv/1' caption='Human β-2 microglobulin (green) complex with MHC I (magenta) and HCMV PP65 nonapeptide (cyan), [[3mrb]]'> | ||
| - | [[Beta-2 microglobulin]] ('''B2M''') is a component of MHC class I system. B2M associates with MHC class I α chain, CD1 and Qa. Loss of B2M function causes iron excess. <ref>PMID:21131979</ref> For more details, see: [[Human beta two microglobulin]]. | + | [[Beta-2 microglobulin]] ('''B2M''') is a component of MHC class I system. B2M associates with MHC class I α chain, CD1 and Qa. Loss of B2M function causes iron excess. <ref>PMID:21131979</ref> For more details, see: [[Human beta two microglobulin]] and [[Molecular playground/beta 2 microglobulin]]. |
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[[Image:MHC Class 1.png|thumb|200px|left|Diagram of MHC I Complex]] | [[Image:MHC Class 1.png|thumb|200px|left|Diagram of MHC I Complex]] | ||
Revision as of 10:23, 26 December 2019
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References
- ↑ Liu C, Sawaya MR, Eisenberg D. beta-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkages. Nat Struct Mol Biol. 2011 Jan;18(1):49-55. Epub 2010 Dec 5. PMID:21131979 doi:10.1038/nsmb.1948
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