6pof
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of human ATP citrate lyase== | |
| - | + | <StructureSection load='6pof' size='340' side='right'caption='[[6pof]], [[Resolution|resolution]] 4.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6pof]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6POF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6POF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ATP_citrate_synthase ATP citrate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.3.8 2.3.3.8] </span></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pof OCA], [http://pdbe.org/6pof PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pof RCSB], [http://www.ebi.ac.uk/pdbsum/6pof PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pof ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ACLY_HUMAN ACLY_HUMAN]] ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine.<ref>PMID:23932781</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: ATP citrate synthase]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ronen, M]] | ||
| + | [[Category: Xuepeng, W]] | ||
| + | [[Category: Apo]] | ||
| + | [[Category: Lyase]] | ||
Revision as of 08:20, 1 January 2020
Structure of human ATP citrate lyase
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