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6tas

From Proteopedia

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m (Protected "6tas" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6tas is ON HOLD
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==Structure of the two-fold capsomer of the dArc1 capsid==
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<StructureSection load='6tas' size='340' side='right'caption='[[6tas]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6tas]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TAS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TAS FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tas OCA], [http://pdbe.org/6tas PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tas RCSB], [http://www.ebi.ac.uk/pdbsum/6tas PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tas ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ARC1_DROME ARC1_DROME]] Master regulator of synaptic plasticity that self-assembles into virion-like capsids that encapsulate RNAs and mediate intercellular RNA transfer from motorneurons to muscles (PubMed:29328915). Arc1 protein is released from motorneurons in extracellular vesicles that mediate the transfer of Arc1 mRNA into muscle cells, where Arc1 mRNA can undergo activity-dependent translation (PubMed:29328915). Intercellular transfer od Arc1 mRNA is required for synaptic plasticity at the neuromuscular junction (PubMed:29328915). May play a role in energy balance: required for regulation of body fat by a specific population of brain neurons, named E347, that are necessary and sufficient for proper body fat storage (PubMed:26209258).<ref>PMID:26209258</ref> <ref>PMID:29328915</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Briggs, J A.G]]
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[[Category: Erlendsson, S]]
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[[Category: Morado, D R]]
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[[Category: Shepherd, J D]]
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[[Category: Darc]]
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[[Category: Gag]]
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[[Category: Virus]]
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[[Category: Virus like particle]]
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[[Category: Vlp]]

Revision as of 08:25, 1 January 2020

Structure of the two-fold capsomer of the dArc1 capsid

PDB ID 6tas

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