6uc0
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Isolated S3D-cofilin bound to an actin filament== | |
| - | + | <StructureSection load='6uc0' size='340' side='right'caption='[[6uc0]], [[Resolution|resolution]] 7.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6uc0]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UC0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UC0 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6vao|6vao]], [[6vau|6vau]], [[6uby|6uby]], [[6uc4|6uc4]]</td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6uc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uc0 OCA], [http://pdbe.org/6uc0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6uc0 RCSB], [http://www.ebi.ac.uk/pdbsum/6uc0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6uc0 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT]] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. [[http://www.uniprot.org/uniprot/COF1_HUMAN COF1_HUMAN]] Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization.<ref>PMID:15580268</ref> <ref>PMID:21834987</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Oryctolagus cuniculus]] | ||
| + | [[Category: Bibeau, J P]] | ||
[[Category: Cao, W]] | [[Category: Cao, W]] | ||
| - | [[Category: | + | [[Category: Cruz, E M.De La]] |
| - | [[Category: | + | [[Category: Huehn, A R]] |
| - | [[Category: | + | [[Category: Schramm, A C]] |
| - | [[Category: | + | [[Category: Sindelar, C V]] |
| + | [[Category: Cytoskeleton]] | ||
| + | [[Category: Structural protein]] | ||
Revision as of 08:28, 1 January 2020
Isolated S3D-cofilin bound to an actin filament
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