6nju

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'''Unreleased structure'''
 
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The entry 6nju is ON HOLD until Paper Publication
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==Mouse endonuclease G mutant H97A bound to A-DNA==
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<StructureSection load='6nju' size='340' side='right'caption='[[6nju]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
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Authors: Vander Zanden, C.M., Ho, E.N., Czarny, R.S., Robertson, A.B., Ho, P.S.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6nju]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NJU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NJU FirstGlance]. <br>
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Description: Mouse endonuclease G mutant H97A bound to A-DNA
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nju OCA], [http://pdbe.org/6nju PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nju RCSB], [http://www.ebi.ac.uk/pdbsum/6nju PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nju ProSAT]</span></td></tr>
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[[Category: Ho, P.S]]
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</table>
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[[Category: Czarny, R.S]]
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== Function ==
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[[Category: Robertson, A.B]]
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[[http://www.uniprot.org/uniprot/NUCG_MOUSE NUCG_MOUSE]] Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA (By similarity).
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[[Category: Vander Zanden, C.M]]
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__TOC__
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[[Category: Ho, E.N]]
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Czarny, R S]]
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[[Category: Ho, E N]]
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[[Category: Ho, P S]]
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[[Category: Robertson, A B]]
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[[Category: Zanden, C M.Vander]]
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[[Category: Complex]]
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[[Category: Endonuclease]]
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[[Category: Recombination]]

Revision as of 07:34, 8 January 2020

Mouse endonuclease G mutant H97A bound to A-DNA

PDB ID 6nju

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