6ofc

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-	'''Unreleased structure'''
-	The entry 6ofc is ON HOLD until Paper Publication	+	==Crystal structure of M. tuberculosis glutamine-dependent NAD+ synthetase complexed with Sulfonamide derivative 1, pyrophosphate, and glutamine==
-		+	<StructureSection load='6ofc' size='340' side='right'caption='[[6ofc]], [[Resolution|resolution]] 3.14&Aring;' scene=''>
-	Authors:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6ofc]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OFC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6OFC FirstGlance]. <br>
-	Description:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GLN:GLUTAMINE'>GLN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=SFH:5-O-[(pyridine-3-carbonyl)sulfamoyl]adenosine'>SFH</scene></td></tr>
-	[[Category: Unreleased Structures]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6ofb|6ofb]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_synthase_(glutamine-hydrolyzing) NAD(+) synthase (glutamine-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.5.1 6.3.5.1] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ofc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ofc OCA], [http://pdbe.org/6ofc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ofc RCSB], [http://www.ebi.ac.uk/pdbsum/6ofc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ofc ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NADE_MYCTO NADE_MYCTO]] Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.[HAMAP-Rule:MF_02090]
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Large Structures]]
		+	[[Category: Chuenchor, W]]
		+	[[Category: Doukov, T I]]
		+	[[Category: Gerratana, B]]
		+	[[Category: Ammonia tunneling]]
		+	[[Category: Atp-binding]]
		+	[[Category: Enzyme]]
		+	[[Category: Gat]]
		+	[[Category: Glutaminase]]
		+	[[Category: Glutamine-amido transferase]]
		+	[[Category: Glutamine-dependent nad+ synthetase]]
		+	[[Category: Inhibitor complex]]
		+	[[Category: Ligase]]
		+	[[Category: Nad synthetase 1]]
		+	[[Category: Nad+ synthetase]]
		+	[[Category: Nucleotide-binding]]
		+	[[Category: Tuberculosis]]

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Revision as of 07:36, 8 January 2020

Crystal structure of M. tuberculosis glutamine-dependent NAD+ synthetase complexed with Sulfonamide derivative 1, pyrophosphate, and glutamine

spinqualitylabelsall models PDB ID 6ofc Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Structural highlights 6ofc is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: , , , , Related: 6ofb Activity: NAD(+) synthase (glutamine-hydrolyzing), with EC number 6.3.5.1 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [NADE_MYCTO] Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.[HAMAP-Rule:MF_02090] Contents 1 Structural highlights 2 Function