6otd

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'''Unreleased structure'''
 
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The entry 6otd is ON HOLD until Paper Publication
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==Globin sensor domain of AfGcHK in monomeric form, with imidazole==
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<StructureSection load='6otd' size='340' side='right'caption='[[6otd]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6otd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OTD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6OTD FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ohe|5ohe]], [[5ohf|5ohf]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6otd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6otd OCA], [http://pdbe.org/6otd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6otd RCSB], [http://www.ebi.ac.uk/pdbsum/6otd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6otd ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/GCHK_ANADF GCHK_ANADF]] Member of the two-component regulatory system GcHK/Anae109_2439. Autophosphorylates in response to oxygen availability, and then transfers the phosphate group to a conserved Asp residue in the receiver domains of the cognate response regulator Anae109_2439, resulting in its activation.<ref>PMID:21852234</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Histidine kinase]]
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[[Category: Large Structures]]
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[[Category: Dohnalek, J]]
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[[Category: Kolenko, P]]
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[[Category: Lengalova, A]]
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[[Category: Martinkova, M]]
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[[Category: Skalova, T]]
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[[Category: Stranava, M]]
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[[Category: Globin domain]]
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[[Category: Globin sensor domain]]
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[[Category: Heme]]
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[[Category: Imidazole]]
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[[Category: Oxygen sensor]]
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[[Category: Sensor protein]]
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[[Category: Transferase]]

Revision as of 07:36, 8 January 2020

Globin sensor domain of AfGcHK in monomeric form, with imidazole

PDB ID 6otd

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