4zy1

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{{Large structure}}
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==X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10r==
==X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10r==
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<StructureSection load='4zy1' size='340' side='right' caption='[[4zy1]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='4zy1' size='340' side='right'caption='[[4zy1]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4zy1]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZY1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZY1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4zy1]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Plafq Plafq]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZY1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZY1 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=4U5:N-{(1R)-2-(HYDROXYAMINO)-1-[4-(1-METHYL-1H-PYRAZOL-4-YL)PHENYL]-2-OXOETHYL}-2,2-DIMETHYLPROPANAMIDE'>4U5</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=4U5:N-{(1R)-2-(HYDROXYAMINO)-1-[4-(1-METHYL-1H-PYRAZOL-4-YL)PHENYL]-2-OXOETHYL}-2,2-DIMETHYLPROPANAMIDE'>4U5</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3kqz|3kqz]], [[4zx8|4zx8]], [[4zx9|4zx9]], [[4zy0|4zy0]], [[4zy2|4zy2]], [[4zyq|4zyq]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3kqz|3kqz]], [[4zx8|4zx8]], [[4zx9|4zx9]], [[4zy0|4zy0]], [[4zy2|4zy2]], [[4zyq|4zyq]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zy1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zy1 OCA], [http://pdbe.org/4zy1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zy1 RCSB], [http://www.ebi.ac.uk/pdbsum/4zy1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zy1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zy1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zy1 OCA], [http://pdbe.org/4zy1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zy1 RCSB], [http://www.ebi.ac.uk/pdbsum/4zy1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zy1 ProSAT]</span></td></tr>
</table>
</table>
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{{Large structure}}
 
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Leucyl aminopeptidase]]
[[Category: Leucyl aminopeptidase]]
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[[Category: Plafq]]
[[Category: Drinkwater, N]]
[[Category: Drinkwater, N]]
[[Category: McGowan, S]]
[[Category: McGowan, S]]

Revision as of 07:55, 8 January 2020

X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10r

PDB ID 4zy1

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