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6cfq

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==Crystal structure of the D141N variant of catalase-peroxidase from B. pseudomallei with INH bound==
==Crystal structure of the D141N variant of catalase-peroxidase from B. pseudomallei with INH bound==
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<StructureSection load='6cfq' size='340' side='right' caption='[[6cfq]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
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<StructureSection load='6cfq' size='340' side='right'caption='[[6cfq]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6cfq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CFQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CFQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6cfq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pseudomallei"_whitmore_1913 "bacillus pseudomallei" whitmore 1913]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CFQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CFQ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NIZ:PYRIDINE-4-CARBOHYDRAZIDE'>NIZ</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NIZ:PYRIDINE-4-CARBOHYDRAZIDE'>NIZ</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">katG, BOC41_00140, BOC42_10690, DP46_2227, DP49_6664 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28450 "Bacillus pseudomallei" Whitmore 1913])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase_peroxidase Catalase peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.21 1.11.1.21] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase_peroxidase Catalase peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.21 1.11.1.21] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cfq OCA], [http://pdbe.org/6cfq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cfq RCSB], [http://www.ebi.ac.uk/pdbsum/6cfq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cfq ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cfq OCA], [http://pdbe.org/6cfq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cfq RCSB], [http://www.ebi.ac.uk/pdbsum/6cfq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cfq ProSAT]</span></td></tr>
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== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/A0A095KYK6_BURPE A0A095KYK6_BURPE]] Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.[HAMAP-Rule:MF_01961][SAAS:SAAS00704213]
[[http://www.uniprot.org/uniprot/A0A095KYK6_BURPE A0A095KYK6_BURPE]] Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.[HAMAP-Rule:MF_01961][SAAS:SAAS00704213]
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==See Also==
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*[[Catalase 3D structures|Catalase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus pseudomallei whitmore 1913]]
[[Category: Catalase peroxidase]]
[[Category: Catalase peroxidase]]
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[[Category: Large Structures]]
[[Category: Loewen, P C]]
[[Category: Loewen, P C]]
[[Category: Catalase]]
[[Category: Catalase]]

Revision as of 08:42, 8 January 2020

Crystal structure of the D141N variant of catalase-peroxidase from B. pseudomallei with INH bound

PDB ID 6cfq

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