This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6cvf
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with cytidine diphosphate== | |
| + | <StructureSection load='6cvf' size='340' side='right'caption='[[6cvf]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6cvf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CVF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CVF FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3fgn|3fgn]], [[3fpa|3fpa]], [[3fmi|3fmi]], [[3fmf|3fmf]], [[4wop|4wop]], [[6cve|6cve]], [[6cvu|6cvu]], [[6cvv|6cvv]], [[6czb|6czb]], [[6czc|6czc]], [[6czd|6czd]], [[6cze|6cze]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bioD, Rv1570, MTCY336.33c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dethiobiotin_synthase Dethiobiotin synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.3.3 6.3.3.3] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cvf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cvf OCA], [http://pdbe.org/6cvf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cvf RCSB], [http://www.ebi.ac.uk/pdbsum/6cvf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cvf ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BIOD_MYCTU BIOD_MYCTU]] Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring.<ref>PMID:20565114</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Dethiobiotin synthetase 3D structures|Dethiobiotin synthetase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Bruning, J | + | </StructureSection> |
| - | [[Category: Thompson, A | + | [[Category: Dethiobiotin synthase]] |
| - | [[Category: Wegener, K | + | [[Category: Large Structures]] |
| + | [[Category: Myctu]] | ||
| + | [[Category: Bruning, J B]] | ||
| + | [[Category: Polyak, S W]] | ||
| + | [[Category: Thompson, A P]] | ||
| + | [[Category: Wegener, K L]] | ||
| + | [[Category: Enzyme]] | ||
| + | [[Category: Nucleotide triphosphate binding]] | ||
| + | [[Category: Synthetase]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 08:46, 8 January 2020
Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with cytidine diphosphate
| |||||||||||
