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6mjy

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'''Unreleased structure'''
 
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The entry 6mjy is ON HOLD until Paper Publication
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==M. thermoresistible GuaB2 delta-CBS in complex with 6Cl-IMP==
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<StructureSection load='6mjy' size='340' side='right'caption='[[6mjy]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
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Authors: Ascher, D.B., Pacitto, A., Blundell, T.L.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6mjy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_19527 Atcc 19527]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MJY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MJY FirstGlance]. <br>
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Description: M. thermoresistible GuaB2 delta-CBS in complex with 6Cl-IMP
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CPR:6-CHLOROPURINE+RIBOSIDE,+5-MONOPHOSPHATE'>CPR</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">guaB, RMCT_0580 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1797 ATCC 19527])</td></tr>
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[[Category: Blundell, T.L]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mjy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mjy OCA], [http://pdbe.org/6mjy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mjy RCSB], [http://www.ebi.ac.uk/pdbsum/6mjy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mjy ProSAT]</span></td></tr>
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[[Category: Ascher, D.B]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/A0A100XBM0_MYCTH A0A100XBM0_MYCTH]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964]
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__TOC__
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</StructureSection>
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[[Category: Atcc 19527]]
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[[Category: Large Structures]]
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[[Category: Ascher, D B]]
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[[Category: Blundell, T L]]
[[Category: Pacitto, A]]
[[Category: Pacitto, A]]
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[[Category: Complex]]
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[[Category: Fragment]]
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[[Category: Impdh]]
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[[Category: Oxidoreductase]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]

Revision as of 09:05, 8 January 2020

M. thermoresistible GuaB2 delta-CBS in complex with 6Cl-IMP

PDB ID 6mjy

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