Sandbox Reserved 1092

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== Disease/Research ==
== Disease/Research ==
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Myostatin <ref name="edumont">Université de Montpellier. Physiologie et médecien fondamentale du coeur et des muscles : myostatine. [https://u1046.edu.umontpellier.fr/163-2/abrege-des-proteines-musculaires/myostatine/]</ref> is a protein that has a control over muscle development: it is a negative regulator of squeletics muscles. It has a very important role during the development of the animals but also during its whole life. It is a very important protein that is very conserved from zebra fish to humans <ref>PMC:2647158</ref> and so it has to be very well regulated. Indeed, there are many ways that regulates the action of this protein and at many scales.
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Myostatin <ref name="edumont">Université de Montpellier. Physiologie et médecien fondamentale du coeur et des muscles : myostatine. [https://u1046.edu.umontpellier.fr/163-2/abrege-des-proteines-musculaires/myostatine/]</ref> is a protein that has a control over muscle development: it is a negative regulator of squeletics muscles. It has a very important role during the development of the animals but also during its whole life. It is a very important protein that is very conserved from zebra fish to humans <ref>PMID:2647158</ref> and so it has to be very well regulated. Indeed, there are many ways that regulates the action of this protein and at many scales.

Revision as of 15:50, 11 January 2020

This Sandbox is Reserved from 25/11/2019, through 30/9/2020 for use in the course "Structural Biology" taught by Bruno Kieffer at the University of Strasbourg, ESBS. This reservation includes Sandbox Reserved 1091 through Sandbox Reserved 1115.
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5JI1 : Myostatin (GDF8)

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References

  1. ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
  3. ↑ Université de Montpellier. Physiologie et médecien fondamentale du coeur et des muscles : myostatine. [1]
  4. ↑ Rajaniemi HJ, Keinanen KP, Kellokumpu S, Petaja-Repo UE, Metsikko MK. Molecular structure of the luteinizing hormone receptor. Biol Reprod. 1989 Jan;40(1):1-12. doi: 10.1095/biolreprod40.1.1. PMID:2647158 doi:http://dx.doi.org/10.1095/biolreprod40.1.1
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