Im7

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Im7 is a [[Colicin Immunity Protein]] that binds to the nuclease domain of [[Colicin E7]], in order to protect the cell producing the [[Colicin]] from the [[DNase Activity]]. When it binds to colicin E7 it physically blocks off the major dsDNA binding sites<ref> PMID: 14962381 </ref>.
Im7 is a [[Colicin Immunity Protein]] that binds to the nuclease domain of [[Colicin E7]], in order to protect the cell producing the [[Colicin]] from the [[DNase Activity]]. When it binds to colicin E7 it physically blocks off the major dsDNA binding sites<ref> PMID: 14962381 </ref>.
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<Structure load='7cei' size='350' frame='true' align='right' caption='' />
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<Structure load='7cei' size='350' frame='true' align='right' caption='Im7 (grey) complex with colicin E7 (green) and Zn+2 ion (grey) (PDB code 7cei]])' />
This structure shows the <scene name='Im7/Im7/1'>Immunity protein</scene> bound to the <scene name='Im7/Cole7c/1'>ColE7 cytotoxic domain</scene>.
This structure shows the <scene name='Im7/Im7/1'>Immunity protein</scene> bound to the <scene name='Im7/Cole7c/1'>ColE7 cytotoxic domain</scene>.

Revision as of 10:46, 12 January 2020

Im7 is a Colicin Immunity Protein that binds to the nuclease domain of Colicin E7, in order to protect the cell producing the Colicin from the DNase Activity. When it binds to colicin E7 it physically blocks off the major dsDNA binding sites[1].

Im7 (grey) complex with colicin E7 (green) and Zn+2 ion (grey) (PDB code 7cei]])

Drag the structure with the mouse to rotate

This structure shows the bound to the .

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Gemma McGoldrick, Jaime Prilusky

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