SAM-dependent methyltransferase
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
The <scene name='51/510230/Cv/5'>core of the SDM fold contains alternating β strands and α helices</scene>. SDM <scene name='51/510230/Cv/6'>active site is located between the 2 monomers</scene><ref>PMID:20876132</ref>. Water molecules are shown as red spheres. | The <scene name='51/510230/Cv/5'>core of the SDM fold contains alternating β strands and α helices</scene>. SDM <scene name='51/510230/Cv/6'>active site is located between the 2 monomers</scene><ref>PMID:20876132</ref>. Water molecules are shown as red spheres. | ||
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| + | ==3D structures of SAM-dependent methyltrasferase== | ||
| + | [[SAM-dependent methyltrasferase 3D structures]] | ||
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</StructureSection> | </StructureSection> | ||
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**[[2ybo]] – PsaSDM + SAH – ''Pseudomonas aeruginosa'' <br /> | **[[2ybo]] – PsaSDM + SAH – ''Pseudomonas aeruginosa'' <br /> | ||
**[[2ybq]] – PsaSDM + SAH + uroporphyrinogen <br /> | **[[2ybq]] – PsaSDM + SAH + uroporphyrinogen <br /> | ||
| + | **[[6uak]] – SDM + SAH – ''Lachnospiraceae bacterium'' <br /> | ||
*Chemotaxis receptor methyltransferase (CheR) | *Chemotaxis receptor methyltransferase (CheR) | ||
Revision as of 08:59, 21 January 2020
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3D structures of SAM-dependent methyltrasferase
Updated on 21-January-2020
References
- ↑ Struck AW, Thompson ML, Wong LS, Micklefield J. S-adenosyl-methionine-dependent methyltransferases: highly versatile enzymes in biocatalysis, biosynthesis and other biotechnological applications. Chembiochem. 2012 Dec 21;13(18):2642-55. doi: 10.1002/cbic.201200556. Epub 2012, Nov 23. PMID:23180741 doi:http://dx.doi.org/10.1002/cbic.201200556
- ↑ Djordjevic S, Stock AM. Chemotaxis receptor recognition by protein methyltransferase CheR. Nat Struct Biol. 1998 Jun;5(6):446-50. PMID:9628482
- ↑ Lee JH, Bae B, Kuemin M, Circello BT, Metcalf WW, Nair SK, van der Donk WA. Characterization and structure of DhpI, a phosphonate O-methyltransferase involved in dehydrophos biosynthesis. Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17557-62. Epub 2010 Sep 27. PMID:20876132 doi:10.1073/pnas.1006848107
