6lf7
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the complex of goat lactoperoxidase with hypothiocyanite and hydrogen peroxide at 1.79 A resolution.== | |
| - | + | <StructureSection load='6lf7' size='340' side='right'caption='[[6lf7]], [[Resolution|resolution]] 1.79Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6lf7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4n7a 4n7a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LF7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6LF7 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OSM:1-(OXIDOSULFANYL)METHANAMINE'>OSM</scene>, <scene name='pdbligand=PEO:HYDROGEN+PEROXIDE'>PEO</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peroxidase Peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.7 1.11.1.7] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6lf7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lf7 OCA], [http://pdbe.org/6lf7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6lf7 RCSB], [http://www.ebi.ac.uk/pdbsum/6lf7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6lf7 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PERL_CAPHI PERL_CAPHI]] Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN) (PubMed:10894086). May protect the udder from infection and promote growth in newborns. Inhibits growth of several fungi including A.niger, Trichoderma species, C.cassicola, P.meadii and C.salmonicolor (PubMed:10894086). Does not have anti-fungal activity towards C.albicans and Pythium species (PubMed:10894086). Inhibits growth of several Gram-positive bacteria including some Staphylococcus species and Gram-negative bacteria including E.coli, P.aeruginosa and some Salmonella species (PubMed:10894086).<ref>PMID:10894086</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Capra hircus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Peroxidase]] | ||
[[Category: Bhushan, A]] | [[Category: Bhushan, A]] | ||
| - | [[Category: | + | [[Category: Kaur, P]] |
| + | [[Category: Sharma, S]] | ||
| + | [[Category: Singh, A]] | ||
| + | [[Category: Singh, A K]] | ||
| + | [[Category: Singh, R P]] | ||
| + | [[Category: Singh, T P]] | ||
[[Category: Sinha, M]] | [[Category: Sinha, M]] | ||
| + | [[Category: Tyagi, T K]] | ||
[[Category: Viswanathan, V]] | [[Category: Viswanathan, V]] | ||
| - | [[Category: | + | [[Category: Oxidoreductase]] |
| - | [[Category: | + | [[Category: Peroxide family]] |
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| - | + | ||
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Revision as of 16:04, 22 January 2020
Crystal structure of the complex of goat lactoperoxidase with hypothiocyanite and hydrogen peroxide at 1.79 A resolution.
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Categories: Capra hircus | Large Structures | Peroxidase | Bhushan, A | Kaur, P | Sharma, S | Singh, A | Singh, A K | Singh, R P | Singh, T P | Sinha, M | Tyagi, T K | Viswanathan, V | Oxidoreductase | Peroxide family
