This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6hzn
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human dermatan sulfate epimerase 1== | |
| - | + | <StructureSection load='6hzn' size='340' side='right'caption='[[6hzn]], [[Resolution|resolution]] 2.41Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6hzn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HZN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HZN FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chondroitin-glucuronate_5-epimerase Chondroitin-glucuronate 5-epimerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.19 5.1.3.19] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hzn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hzn OCA], [http://pdbe.org/6hzn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hzn RCSB], [http://www.ebi.ac.uk/pdbsum/6hzn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hzn ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/DSE_HUMAN DSE_HUMAN]] Musculocontractural Ehlers-Danlos syndrome. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DSE_HUMAN DSE_HUMAN]] Converts D-glucuronic acid to L-iduronic acid (IdoUA) residues.<ref>PMID:16505484</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Chondroitin-glucuronate 5-epimerase]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ellervik, U]] | ||
| + | [[Category: Hasan, M]] | ||
[[Category: Malmstrom, A]] | [[Category: Malmstrom, A]] | ||
| + | [[Category: Mueller, U]] | ||
[[Category: Tykesson, E]] | [[Category: Tykesson, E]] | ||
| - | [[Category: Hasan, M]] | ||
[[Category: Unge, J]] | [[Category: Unge, J]] | ||
| - | [[Category: Mueller, U]] | ||
| - | [[Category: Ellervik, U]] | ||
[[Category: Westergren-Thorsson, G]] | [[Category: Westergren-Thorsson, G]] | ||
| + | [[Category: Biosynthetic protein]] | ||
| + | [[Category: Chondroitin sulfate]] | ||
| + | [[Category: Dermatan sulfate]] | ||
| + | [[Category: Epimerase]] | ||
| + | [[Category: Glycosaminoglycan]] | ||
| + | [[Category: Golgi]] | ||
| + | [[Category: Isomerase]] | ||
Revision as of 16:05, 22 January 2020
Crystal structure of human dermatan sulfate epimerase 1
| |||||||||||
