6j7f
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Complex of GGTaseIII, farnesyl-Ykt6 (C-terminal methylated), and GGPP== | |
| - | + | <StructureSection load='6j7f' size='340' side='right'caption='[[6j7f]], [[Resolution|resolution]] 2.88Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6j7f]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J7F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6J7F FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DPO:DIPHOSPHATE'>DPO</scene>, <scene name='pdbligand=FAR:FARNESYL'>FAR</scene>, <scene name='pdbligand=GER:GERAN-8-YL+GERAN'>GER</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CMT:O-METHYLCYSTEINE'>CMT</scene></td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein_geranylgeranyltransferase_type_II Protein geranylgeranyltransferase type II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.60 2.5.1.60] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6j7f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j7f OCA], [http://pdbe.org/6j7f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6j7f RCSB], [http://www.ebi.ac.uk/pdbsum/6j7f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6j7f ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/YKT6_HUMAN YKT6_HUMAN]] Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.<ref>PMID:15215310</ref> <ref>PMID:9211930</ref> [[http://www.uniprot.org/uniprot/PGTB2_HUMAN PGTB2_HUMAN]] Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A. | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Protein geranylgeranyltransferase type II]] | ||
| + | [[Category: Fukai, S]] | ||
| + | [[Category: Goto-Ito, S]] | ||
| + | [[Category: Sato, Y]] | ||
| + | [[Category: Yamagata, A]] | ||
| + | [[Category: Lipid binding protein]] | ||
| + | [[Category: Lipid transferase]] | ||
Revision as of 16:07, 22 January 2020
Complex of GGTaseIII, farnesyl-Ykt6 (C-terminal methylated), and GGPP
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