6lk0

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'''Unreleased structure'''
 
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The entry 6lk0 is ON HOLD
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==Crystal structure of human wild type TRIP13==
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<StructureSection load='6lk0' size='340' side='right'caption='[[6lk0]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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Authors: Wang, Y., Huang, J., Li, B., Xue, H., Tricot, G., Hu, L., Xu, Z., Sun, X., Chang, S., Gao, L., Tao, Y., Xu, H., Xie, Y., Xiao, W., Yu, D., Kong, Y., Chen, G., Sun, X., Lian, F., Zhang, N., Wu, X., Mao, Z., Zhan, F., Zhu, W., Shi, J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6lk0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LK0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6LK0 FirstGlance]. <br>
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Description: Crystal structure of human wild type TRIP13
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6lk0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lk0 OCA], [http://pdbe.org/6lk0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6lk0 RCSB], [http://www.ebi.ac.uk/pdbsum/6lk0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6lk0 ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Wu, X]]
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== Function ==
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[[http://www.uniprot.org/uniprot/PCH2_HUMAN PCH2_HUMAN]] Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity).
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Chang, S]]
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[[Category: Chen, G]]
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[[Category: Gao, L]]
[[Category: Hu, L]]
[[Category: Hu, L]]
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[[Category: Xue, H]]
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[[Category: Huang, J]]
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[[Category: Zhang, N]]
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[[Category: Kong, Y]]
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[[Category: Wang, Y]]
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[[Category: Li, B]]
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[[Category: Xie, Y]]
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[[Category: Tao, Y]]
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[[Category: Lian, F]]
[[Category: Lian, F]]
[[Category: Mao, Z]]
[[Category: Mao, Z]]
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[[Category: Chen, G]]
 
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[[Category: Zhan, F]]
 
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[[Category: Kong, Y]]
 
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[[Category: Xu, Z]]
 
[[Category: Shi, J]]
[[Category: Shi, J]]
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[[Category: Zhu, W]]
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[[Category: Sun, X]]
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[[Category: Tao, Y]]
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[[Category: Tricot, G]]
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[[Category: Wang, Y]]
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[[Category: Wu, X]]
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[[Category: Xiao, W]]
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[[Category: Xie, Y]]
[[Category: Xu, H]]
[[Category: Xu, H]]
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[[Category: Huang, J]]
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[[Category: Xu, Z]]
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[[Category: Sun, X]]
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[[Category: Xue, H]]
[[Category: Yu, D]]
[[Category: Yu, D]]
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[[Category: Gao, L]]
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[[Category: Zhan, F]]
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[[Category: Chang, S]]
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[[Category: Zhang, N]]
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[[Category: Xiao, W]]
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[[Category: Zhu, W]]
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[[Category: Tricot, G]]
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[[Category: Aaa+ atpase]]
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[[Category: Li, B]]
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[[Category: Atp-bound]]
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[[Category: Conformation dynamic]]
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[[Category: Hexamer helical filament]]
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[[Category: Oncoprotein]]

Revision as of 16:09, 22 January 2020

Crystal structure of human wild type TRIP13

PDB ID 6lk0

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