User:Ivan E. Wang/Sandbox 1
From Proteopedia
(Difference between revisions)
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'''Retinal Pigment Epithelium 65 (Retinoid Isomerohydrolase) complex with (''R''/''S'')-emixustat and palmitate''' | '''Retinal Pigment Epithelium 65 (Retinoid Isomerohydrolase) complex with (''R''/''S'')-emixustat and palmitate''' | ||
| - | <StructureSection load='4rsc | + | <StructureSection load='4rsc' size='340' side='right' caption='Emixustat bound in the active site of RPE65' scene=''> |
Retinal pigment epithelium 65 (RPE65) also known as retinoid isomerohydrolase is a 65 kDa enzyme located within the human retinal pigment epithelium cells responsible for the chemical conversion of ''all-trans''-retinyl ester to ''11-cis''-retinol in the visual cycle. | Retinal pigment epithelium 65 (RPE65) also known as retinoid isomerohydrolase is a 65 kDa enzyme located within the human retinal pigment epithelium cells responsible for the chemical conversion of ''all-trans''-retinyl ester to ''11-cis''-retinol in the visual cycle. | ||
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== Exogenous Ligand == | == Exogenous Ligand == | ||
| - | <StructureSection load='4ryy | + | <StructureSection load='4ryy' size='340' side='right' caption='(''R'')-emixustat bound in the active site of RPE65' scene=''> |
=== (''R'')-Emixustat (ACU-4429) === | === (''R'')-Emixustat (ACU-4429) === | ||
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</StructureSection> | </StructureSection> | ||
| - | <StructureSection load=' | + | <StructureSection load='4ryz' size='340' side='right' caption='(''S'')-emixustat bound in the active site of RPE65' scene=''> |
=== (''S'')-Emixustat === | === (''S'')-Emixustat === | ||
(PLACEHOLDER) | (PLACEHOLDER) | ||
Revision as of 22:48, 28 January 2020
Retinal Pigment Epithelium 65 (Retinoid Isomerohydrolase) complex with (R/S)-emixustat and palmitate
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Contents |
Protein-Ligand Interaction
Endogenous Ligand
(PLACEHOLDER)
Exogenous Ligand
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R/S Enantiomers Differences
(PLACEHOLDER)
Disease Implications
(PLACEHOLDER)
Medical Relevance
(PLACEHOLDER)
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
