6hw2
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | The | + | ==The Crystal Structure of CaV beta4c in complex with HP1gamma chromo shadow domains== |
| - | + | <StructureSection load='6hw2' size='340' side='right'caption='[[6hw2]], [[Resolution|resolution]] 1.94Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6hw2]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HW2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HW2 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hw2 OCA], [http://pdbe.org/6hw2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hw2 RCSB], [http://www.ebi.ac.uk/pdbsum/6hw2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hw2 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CBX3_HUMAN CBX3_HUMAN]] Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Hirsch, J A]] | ||
| + | [[Category: Tanner, N]] | ||
| + | [[Category: Tripathy, D R]] | ||
| + | [[Category: Complex]] | ||
| + | [[Category: Transport protein]] | ||
Revision as of 15:24, 29 January 2020
The Crystal Structure of CaV beta4c in complex with HP1gamma chromo shadow domains
| |||||||||||
