6qck

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m (Protected "6qck" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6qck is ON HOLD
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==17beta-hydroxysteroid dehydrogenase 14 variant T205 in complex with FB262==
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<StructureSection load='6qck' size='340' side='right'caption='[[6qck]], [[Resolution|resolution]] 1.68&Aring;' scene=''>
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Authors: Bertoletti, N., Marchais-Oberwinkler, S., Heine, A., Klebe, G.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6qck]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QCK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QCK FirstGlance]. <br>
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Description: 17beta-hydroxysteroid dehydrogenase 14 variant T205 in complex with FB262
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=HWK:2-[2-(1,3-benzodioxol-2-yl)ethyl]benzoic+acid'>HWK</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qck FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qck OCA], [http://pdbe.org/6qck PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qck RCSB], [http://www.ebi.ac.uk/pdbsum/6qck PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qck ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/DHB14_HUMAN DHB14_HUMAN]] Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).<ref>PMID:17067289</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Bertoletti, N]]
[[Category: Heine, A]]
[[Category: Heine, A]]
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[[Category: Bertoletti, N]]
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[[Category: Klebe, G]]
[[Category: Marchais-Oberwinkler, S]]
[[Category: Marchais-Oberwinkler, S]]
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[[Category: Klebe, G]]
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[[Category: 17b-hsd14]]
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[[Category: Fragment]]
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[[Category: Oxidoreductase]]
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[[Category: Soaking]]

Revision as of 15:35, 29 January 2020

17beta-hydroxysteroid dehydrogenase 14 variant T205 in complex with FB262

PDB ID 6qck

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