6t2t
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Drosophila melanogaster glutathione S-transferase epsilon 14 in complex with glutathione and 2-methyl-2,4-pentanediol== | |
| - | + | <StructureSection load='6t2t' size='340' side='right'caption='[[6t2t]], [[Resolution|resolution]] 1.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6t2t]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6T2T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6T2T FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6t2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6t2t OCA], [http://pdbe.org/6t2t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6t2t RCSB], [http://www.ebi.ac.uk/pdbsum/6t2t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6t2t ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GSTEE_DROME GSTEE_DROME]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (PubMed:22082028). Essential for ecdysteroid biosynthesis (PubMed:25344753, PubMed:25300303). May be involved in detoxification (PubMed:22082028).<ref>PMID:22082028</ref> <ref>PMID:25300303</ref> <ref>PMID:25344753</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Glutathione transferase]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Gonis, E]] | ||
| + | [[Category: Lindstrom, H]] | ||
| + | [[Category: Mannervik, B]] | ||
| + | [[Category: Neiers, F]] | ||
| + | [[Category: Sjodin, B]] | ||
| + | [[Category: Skerlova, J]] | ||
| + | [[Category: Stenmark, P]] | ||
| + | [[Category: Steroid isomerase]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 15:40, 29 January 2020
Crystal structure of Drosophila melanogaster glutathione S-transferase epsilon 14 in complex with glutathione and 2-methyl-2,4-pentanediol
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