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6tue
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of human indoleamine-2,3-dioxygenase 1 (hIDO) with a complete JK loop== | |
| - | + | <StructureSection load='6tue' size='340' side='right'caption='[[6tue]], [[Resolution|resolution]] 2.61Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6tue]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TUE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TUE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Indoleamine_2,3-dioxygenase Indoleamine 2,3-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.52 1.13.11.52] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tue FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tue OCA], [http://pdbe.org/6tue PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tue RCSB], [http://www.ebi.ac.uk/pdbsum/6tue PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tue ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/I23O1_HUMAN I23O1_HUMAN]] Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.<ref>PMID:17671174</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Indoleamine 2,3-dioxygenase]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mirgaux, M]] | ||
[[Category: Wouters, J]] | [[Category: Wouters, J]] | ||
| - | [[Category: | + | [[Category: Dioxygenase]] |
| + | [[Category: Enzyme]] | ||
| + | [[Category: Heme-binding]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Tryptophan catabolism]] | ||
Revision as of 15:43, 29 January 2020
Structure of human indoleamine-2,3-dioxygenase 1 (hIDO) with a complete JK loop
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