6tkv

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'''Unreleased structure'''
 
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The entry 6tkv is ON HOLD
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==Crystal structure of the human FUT8 in complex with GDP and a biantennary complex N-glycan==
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<StructureSection load='6tkv' size='340' side='right'caption='[[6tkv]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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Authors: Garcia-Garcia, A., Ceballos-Laita, L., Serna, L., Artschwager, R., Reichardt, N.C., Corzana, F., Hurtado-Guerrero, R.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6tkv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TKV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TKV FirstGlance]. <br>
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Description: Crystal structure of a glycosyltransferase complexed to the donor and acceptor substrate
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycoprotein_6-alpha-L-fucosyltransferase Glycoprotein 6-alpha-L-fucosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.68 2.4.1.68] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tkv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tkv OCA], [http://pdbe.org/6tkv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tkv RCSB], [http://www.ebi.ac.uk/pdbsum/6tkv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tkv ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/FUT8_HUMAN FUT8_HUMAN]] Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.<ref>PMID:9133635</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Glycoprotein 6-alpha-L-fucosyltransferase]]
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[[Category: Large Structures]]
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[[Category: Artschwager, R]]
[[Category: Ceballos-Laita, L]]
[[Category: Ceballos-Laita, L]]
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[[Category: Corzana, F]]
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[[Category: Garcia-Garcia, A]]
[[Category: Hurtado-Guerrero, R]]
[[Category: Hurtado-Guerrero, R]]
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[[Category: Garcia-Garcia, A]]
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[[Category: Reichardt, N C]]
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[[Category: Reichardt, N.C]]
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[[Category: Serna, L]]
[[Category: Serna, L]]
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[[Category: Corzana, F]]
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[[Category: Acceptor substrate]]
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[[Category: Artschwager, R]]
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[[Category: Catalysis]]
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[[Category: Glycosyltransferase]]
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[[Category: Sugar binding protein]]
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[[Category: Sugar nucleotide]]

Revision as of 15:43, 29 January 2020

Crystal structure of the human FUT8 in complex with GDP and a biantennary complex N-glycan

PDB ID 6tkv

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