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6uuj
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of PE5-PPE4-EspG3 complex from the type VII (ESX-3) secretion system, space group P212121== | |
| - | + | <StructureSection load='6uuj' size='340' side='right'caption='[[6uuj]], [[Resolution|resolution]] 3.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6uuj]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UUJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UUJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6vhr|6vhr]]</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6uuj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uuj OCA], [http://pdbe.org/6uuj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6uuj RCSB], [http://www.ebi.ac.uk/pdbsum/6uuj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6uuj ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PE05_MYCTU PE05_MYCTU]] Important for the siderophore-mediated iron-acquisition function of ESX-3 (PubMed:26729876). May play a pivotal role in the evasion of host immune response by M.tuberculosis. Mediates production of IL-10 via activation of the p38 and ERK1/2 mitogen-activated protein kinase (MAPK) signaling pathways (PubMed:23284742).<ref>PMID:23284742</ref> <ref>PMID:26729876</ref> [[http://www.uniprot.org/uniprot/PPE04_MYCTU PPE04_MYCTU]] Important for the siderophore-mediated iron-acquisition function of ESX-3.<ref>PMID:26729876</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Korotkov, K V]] | ||
| + | [[Category: Williamson, Z A]] | ||
| + | [[Category: Chaperone]] | ||
| + | [[Category: Protein secretion]] | ||
| + | [[Category: Protein transport]] | ||
Revision as of 15:45, 29 January 2020
Structure of PE5-PPE4-EspG3 complex from the type VII (ESX-3) secretion system, space group P212121
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