1af6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1af6.gif|left|200px]]
[[Image:1af6.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1af6 |SIZE=350|CAPTION= <scene name='initialview01'>1af6</scene>, resolution 2.4&Aring;
+
The line below this paragraph, containing "STRUCTURE_1af6", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLC:GLUCOSE'>GLC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE= LAMB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1af6| PDB=1af6 | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1af6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1af6 OCA], [http://www.ebi.ac.uk/pdbsum/1af6 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1af6 RCSB]</span>
+
-
}}
+
'''MALTOPORIN SUCROSE COMPLEX'''
'''MALTOPORIN SUCROSE COMPLEX'''
Line 27: Line 24:
[[Category: Dutzler, R.]]
[[Category: Dutzler, R.]]
[[Category: Schirmer, T.]]
[[Category: Schirmer, T.]]
-
[[Category: beta barrel]]
+
[[Category: Beta barrel]]
-
[[Category: membrane protein]]
+
[[Category: Membrane protein]]
-
[[Category: specific porin]]
+
[[Category: Specific porin]]
-
[[Category: sucrose]]
+
[[Category: Sucrose]]
-
[[Category: sugar transport]]
+
[[Category: Sugar transport]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 10:11:20 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 18:38:56 2008''
+

Revision as of 07:11, 2 May 2008

Image:1af6.gif

Template:STRUCTURE 1af6

MALTOPORIN SUCROSE COMPLEX


Overview

Maltoporin (LamB) facilitates the diffusion of maltodextrins across the outer membrane of E. coli. The structural basis for the specificity of the channel is investigated by X-ray structure analysis of maltoporin in complex with the disaccharides sucrose, trehalose, and melibiose. The sucrose complex, determined to 2.4 A resolution, shows that the glucosyl moiety is partly inserted into the channel constriction, while the bulky fructosyl residue appears to be hindered to enter the constriction, thus interfering with its further translocation. One of the glucosyl moieties of trehalose is found in a similar position as the glucosyl moiety of sucrose, whereas melibiose appears disordered when bound to maltoporin. A comparison with the previously reported maltoporin-maltose complex sheds light on the basis for sugar discrimination, and explains the different permeation rates observed for the saccharides.

About this Structure

1AF6 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Channel specificity: structural basis for sugar discrimination and differential flux rates in maltoporin., Wang YF, Dutzler R, Rizkallah PJ, Rosenbusch JP, Schirmer T, J Mol Biol. 1997 Sep 12;272(1):56-63. PMID:9299337 Page seeded by OCA on Fri May 2 10:11:20 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1af6"
Personal tools