1yfg
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(New page: 200px<br /> <applet load="1yfg" size="450" color="white" frame="true" align="right" spinBox="true" caption="1yfg, resolution 3.000Å" /> '''YEAST INITIATOR TR...)
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Revision as of 10:39, 8 November 2007
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YEAST INITIATOR TRNA
Overview
A significantly improved molecular model of yeast initiator tRNA, (ytRNA(iMet) has been prepared that gives insight into the structural, basis of eukaryotic initiator tRNA's unique function. This study was made, possible by X-ray data collected at synchrotron radiation sources with the, newly developed technologies of 'imaging plates' and 'storage phosphors'., These data extend beyond the resolution limit of 4.0 A reported previously, to a current limit of 3.0 A and are considerably more accurate. Refinement, of the model against the new data (R factor = 21.5%) clearly reveals a, novel modification and a set of tertiary interactions involving sequence, features characteristic of eukaryotic initiator tRNAs. We hypothesize, these to be the structural elements responsible for part of the special, function of yeast tRNA(iMET).
About this Structure
1YFG is a Protein complex structure of sequences from Saccharomyces cerevisiae. The following page contains interesting information on the relation of 1YFG with [Transfer RNA]. Full crystallographic information is available from OCA.
Reference
The 3 A crystal structure of yeast initiator tRNA: functional implications in initiator/elongator discrimination., Basavappa R, Sigler PB, EMBO J. 1991 Oct;10(10):3105-11. PMID:1915284
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