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1aft

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[[Image:1aft.gif|left|200px]]
[[Image:1aft.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1aft |SIZE=350|CAPTION= <scene name='initialview01'>1aft</scene>
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The line below this paragraph, containing "STRUCTURE_1aft", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE=
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-->
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|DOMAIN=
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{{STRUCTURE_1aft| PDB=1aft | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1aft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1aft OCA], [http://www.ebi.ac.uk/pdbsum/1aft PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1aft RCSB]</span>
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}}
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'''SMALL SUBUNIT C-TERMINAL INHIBITORY PEPTIDE OF MOUSE RIBONUCLEOTIDE REDUCTASE AS BOUND TO THE LARGE SUBUNIT, NMR, 26 STRUCTURES'''
'''SMALL SUBUNIT C-TERMINAL INHIBITORY PEPTIDE OF MOUSE RIBONUCLEOTIDE REDUCTASE AS BOUND TO THE LARGE SUBUNIT, NMR, 26 STRUCTURES'''
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==About this Structure==
==About this Structure==
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1AFT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AFT OCA].
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1AFT is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AFT OCA].
==Reference==
==Reference==
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[[Category: Hamann, C S.]]
[[Category: Hamann, C S.]]
[[Category: Laub, P B.]]
[[Category: Laub, P B.]]
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[[Category: nonstandard type i turn]]
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[[Category: Nonstandard type i turn]]
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[[Category: peptide inhibitor]]
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[[Category: Peptide inhibitor]]
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[[Category: restrained molecular dynamic]]
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[[Category: Restrained molecular dynamic]]
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[[Category: ribonucleotide reductase]]
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[[Category: Ribonucleotide reductase]]
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[[Category: transferred noesy]]
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[[Category: Transferred noesy]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 10:12:42 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 18:39:19 2008''
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Revision as of 07:12, 2 May 2008

Image:1aft.gif

Template:STRUCTURE 1aft

SMALL SUBUNIT C-TERMINAL INHIBITORY PEPTIDE OF MOUSE RIBONUCLEOTIDE REDUCTASE AS BOUND TO THE LARGE SUBUNIT, NMR, 26 STRUCTURES


Overview

The structure of peptide N-AcYTLDADF when bound to the large subunit of mouse ribonucleotide reductase has been elucidated by transfer NOE. This structure suggests a general design for type 1 RR inhibitors.

About this Structure

1AFT is a Single protein structure. Full crystallographic information is available from OCA.

Reference

NMR structure of an inhibitory R2 C-terminal peptide bound to mouse ribonucleotide reductase R1 subunit., Fisher A, Laub PB, Cooperman BS, Nat Struct Biol. 1995 Nov;2(11):951-5. PMID:7583667 Page seeded by OCA on Fri May 2 10:12:42 2008

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