6qgo
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of APT1 S119A mutant bound to palmitic acid.== | |
| - | + | <StructureSection load='6qgo' size='340' side='right'caption='[[6qgo]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6qgo]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QGO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QGO FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6qgn|6qgn]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qgo OCA], [http://pdbe.org/6qgo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qgo RCSB], [http://www.ebi.ac.uk/pdbsum/6qgo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qgo ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LYPA1_HUMAN LYPA1_HUMAN]] Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity and also low lysophospholipase activity.<ref>PMID:20418879</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Audagnotto, M]] | ||
| + | [[Category: Goot, G Van der]] | ||
| + | [[Category: Ho, S]] | ||
| + | [[Category: Marcaida, M J]] | ||
| + | [[Category: Peraro, M Dal]] | ||
| + | [[Category: Pojer, F]] | ||
| + | [[Category: Acyl-protein thioesterase]] | ||
| + | [[Category: Depalmitoylation]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Palmitic acid]] | ||
Revision as of 08:04, 5 February 2020
Crystal structure of APT1 S119A mutant bound to palmitic acid.
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