6qgq

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m (Protected "6qgq" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6qgq is ON HOLD until Paper Publication
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==Crystal structure of APT1 C2S mutant bound to palmitic acid.==
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<StructureSection load='6qgq' size='340' side='right'caption='[[6qgq]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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Authors: Audagnotto, M., Marcaida, M.J., Ho, S., Pojer, F., Van der Goot, G., Dal Peraro, M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6qgq]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QGQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QGQ FirstGlance]. <br>
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Description: Crystal structure of APT1 C2S mutant bound to palmitic acid.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6qgo|6qgo]], [[6qgn|6qgn]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qgq OCA], [http://pdbe.org/6qgq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qgq RCSB], [http://www.ebi.ac.uk/pdbsum/6qgq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qgq ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/LYPA1_HUMAN LYPA1_HUMAN]] Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity and also low lysophospholipase activity.<ref>PMID:20418879</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Audagnotto, M]]
[[Category: Audagnotto, M]]
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[[Category: Goot, G Van der]]
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[[Category: Ho, S]]
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[[Category: Marcaida, M J]]
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[[Category: Peraro, M Dal]]
[[Category: Pojer, F]]
[[Category: Pojer, F]]
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[[Category: Marcaida, M.J]]
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[[Category: Acyl-protein thioesterase]]
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[[Category: Van Der Goot, G]]
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[[Category: Depalmitoylation]]
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[[Category: Ho, S]]
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[[Category: Hydrolase]]
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[[Category: Dal Peraro, M]]
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[[Category: Palmitic acid]]

Revision as of 08:04, 5 February 2020

Crystal structure of APT1 C2S mutant bound to palmitic acid.

PDB ID 6qgq

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