2hvp
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(New page: 200px<br /> <applet load="2hvp" size="450" color="white" frame="true" align="right" spinBox="true" caption="2hvp, resolution 3.0Å" /> '''THREE-DIMENSIONAL ST...)
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Revision as of 10:41, 8 November 2007
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THREE-DIMENSIONAL STRUCTURE OF ASPARTYL PROTEASE FROM HUMAN IMMUNODEFICIENCY VIRUS HIV-1
Overview
The crystal structure of the protease of the human immunodeficiency virus, type (HIV-1), which releases structural proteins and enzymes from viral, polyprotein products, has been determined to 3 A resolution. Large regions, of the protease dimer, including the active site, have structural homology, to the family of microbial aspartyl proteases. The structure suggests a, mechanism for the autoproteolytic release of protease and a role in the, control of virus maturation.
About this Structure
2HVP is a Single protein structure of sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1., Navia MA, Fitzgerald PM, McKeever BM, Leu CT, Heimbach JC, Herber WK, Sigal IS, Darke PL, Springer JP, Nature. 1989 Feb 16;337(6208):615-20. PMID:2645523
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