Symporter
From Proteopedia
(Difference between revisions)
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</StructureSection> | </StructureSection> | ||
- | == 3D Structures of symporter == | ||
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- | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
- | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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- | *D-xylose/H+ symporter | ||
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- | **[[4ja4]], [[4qiq]] – EcSymp – ''Escherichia coli''<BR /> | ||
- | **[[4ja3]], [[6n3i]] – EcSymp (mutant) <BR /> | ||
- | **[[4gby]] – EcSymp + xylose <BR /> | ||
- | **[[4gbz]], [[4gc0]] – EcSymp + glucose derivative<BR /> | ||
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- | *Di-or tripeptide/H+ symporter | ||
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- | **[[4ja4]], [[4xni]], [[4xnj]], [[4d2b]], [[4aps]], [[5d6k]], [[5mmt]], [[5d6k]], [[5oxo]], [[5oxp]], [[5oxq]], [[6eia]], [[6fmr]], [[6fmy]] – StSymp – ''Streptococcus thermophilus''<BR /> | ||
- | **[[4d2d]], [[6ghj]] – StSymp + tripeptide<BR /> | ||
- | **[[4d2c]], [[5d58]], [[5d59]], [[5oxk]], [[5oxl]], [[5oxm]], [[5oxn]] – StSymp + dipeptide<BR /> | ||
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- | *Oligopeptide/H+ symporter | ||
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- | **[[4lep]], [[4tph]], [[6jkc]], [[6jkd]] – SoSymp – ''Shewanella oneidensis''<BR /> | ||
- | **[[6ji1]] – SoSymp – Cryo EM<BR />**[[2xut]] – SoSymp (mutant) <BR /> | ||
- | **[[4tpg]], [[4tpj]] – SoSymp + tripeptide<BR /> | ||
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- | *Bile acid/Na+ symporter | ||
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- | **[[4n7w]] – YfSymp – ''Yersinia frederiksenii''<BR /> | ||
- | **[[4n7x]] – YfSymp (mutant) <BR /> | ||
- | **[[3zuy]] – Symp - ''Neisseria meningitidis''<BR /> | ||
- | **[[3zux]] – Symp (mutant) <BR /> | ||
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- | *L-fucose/H+ symporter | ||
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- | **[[3o7q]] – EcSymp <BR /> | ||
- | **[[3o7p]] – EcSymp (mutant)<BR /> | ||
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- | *Succinate-acetate/H+ symporter | ||
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- | **[[5zug]] – EcSymp <BR /> | ||
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- | *Lactose/H+ symporter | ||
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- | **[[1pv6]] – EcSymp (mutant)<BR /> | ||
- | **[[1pv7]], [[4oaa]] – EcSymp (mutant) + thiodigalactoside<BR /> | ||
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- | *Glucose/Na+ symporter | ||
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- | **[[2xq2]] – VpSymp (mutant) – ''Vibrio parahaemolyticus''<BR /> | ||
- | **[[3dh4]] – VpSymp + galactose <BR /> | ||
- | **[[4m64]] – Symp (mutant) - ''Salmonella typhimurium''<BR /> | ||
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- | *Citrate/Na+ symporter | ||
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- | **[[5a1s]] – Symp + citrate + Na – ''Salmonella enterica''<BR /> | ||
- | **[[5x9r]], [[5xas]], [[5xat]] – KpSymp + citrate + Na – ''Klebsiella pneumoniae''<BR /> | ||
- | **[[4bpq]], [[5xar]] – KpSymp <BR /> | ||
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- | *Sodium/alanine symporter | ||
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- | **[[6csf]], [[6cse]] – Symp + antibody + alanine – ''Methanococcus maripaludis''<BR /> | ||
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- | *Sodium/aspartate symporter | ||
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- | **[[6bat]] – PhSymp + aspartate – ''Pyrococcus horikoshi''i<BR /> | ||
- | **[[6bav]], [[6bau]] – PhSymp (mutant) + cysteine derivative<BR /> | ||
- | **[[6bmi]] – PhSymp (mutant) + serine<BR /> | ||
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- | *Sodium/glutamate symporter | ||
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- | **[[4p6h]], [[4p3j]], [[4p1a]], [[3v8g]], [[3v8f]] – PhSymp <BR /> | ||
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- | *Neurotransmitter/leucine symporter LeuT | ||
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- | **[[5jaf]], [[5jae]] – AaSymp - ''Aquifex aeolicus''<BR /> | ||
- | **[[5jag]] – AaSymp (mutant) <BR /> | ||
- | **[[3gjd]] – AaSymp + Na <BR /> | ||
- | **[[3f48]] – AaSymp + alaine + Na<BR /> | ||
- | **[[3tu0]] – AaSymp (mutant) + alanine + Na <BR /> | ||
- | **[[3f4j]] – AaSymp + glycine + Na<BR /> | ||
- | **[[2a65]], [[3f3e]], [[3usg]], [[3usi]], [[3usj]], [[3usk]] – AaSymp + leucine + Na<BR /> | ||
- | **[[3mpn]], [[3mpq]], [[3gjc]], [[4hmk]], [[4hod]], [[4fxz]] – AaSymp (mutant) + leucine + Na<BR /> | ||
- | **[[3f3a]] – AaSymp + tryptophan + Na <BR /> | ||
- | **[[3qs4]], [[3qs5]], [[3qs6]] – AaSymp (mutant) + tryptophan + Na <BR /> | ||
- | **[[3f3c]] – AaSymp + phenylalanine + Na <BR /> | ||
- | **[[3f3d]], [[3f4i]], [[3usl]], [[3usm]], [[3uso]] – AaSymp + methionine derivative + Na <BR /> | ||
- | **[[4fy0]] – AaSymp (mutant) + methionine + Na <BR /> | ||
- | **[[2qei]] – AaSymp + alaine + clomipramine + Na<BR /> | ||
- | **[[3gwu]] – AaSymp + sertraline + Na<BR /> | ||
- | **[[3gwv]], [[3gww]], [[2qb4]], [[2q6h]], [[2q72]], [[2qju]] – AaSymp + drug + Na<BR /> | ||
- | **[[4mm4]] – AaSymp (mutant) + drug + Na<BR /> | ||
- | **[[3usp]] – AaSymp + glucoside derivative + Na <BR /> | ||
- | **[[3tt1]], [[3tt3]] – AaSymp (mutant) + antibody + Na <BR /> | ||
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- | *Divalent ion/Na+ symporter | ||
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- | **[[5ul7]], [[5ul9]], [[5uld]], [[5ule]], [[4f35]] – Symp + Na – ''Vibrio cholerae''<BR /> | ||
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- | *Purine/H+ symporter | ||
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- | **[[5i6c]] – Symp + xanthine – ''Aspergillus nidulans''<BR /> | ||
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- | *Glutamate/H+ symporter | ||
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- | **[[5dwy]], [[4ky0]] – TkSymp – ''Thermococcus kodakarensis''<BR /> | ||
- | **[[5e9s]] – TkSymp + aspartate<BR /> | ||
- | **[[4oyf]] – PhSymp - ''Pyrococcus horikishii'' <BR /> | ||
- | **[[2nwl]] – PhSymp (mutant) + aspartate<BR /> | ||
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- | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] |
Revision as of 10:38, 12 February 2020
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References
- ↑ Dohan O, De la Vieja A, Paroder V, Riedel C, Artani M, Reed M, Ginter CS, Carrasco N. The sodium/iodide Symporter (NIS): characterization, regulation, and medical significance. Endocr Rev. 2003 Feb;24(1):48-77. PMID:12588808 doi:http://dx.doi.org/10.1210/er.2001-0029
- ↑ Pohlenz J, Refetoff S. Mutations in the sodium/iodide symporter (NIS) gene as a cause for iodide transport defects and congenital hypothyroidism. Biochimie. 1999 May;81(5):469-76. PMID:10403177
- ↑ Lyons JA, Parker JL, Solcan N, Brinth A, Li D, Shah ST, Caffrey M, Newstead S. Structural basis for polyspecificity in the POT family of proton-coupled oligopeptide transporters. EMBO Rep. 2014 Jun 10. pii: e201338403. PMID:24916388 doi:http://dx.doi.org/10.15252/embr.201338403