6vip

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "6vip" [edit=sysop:move=sysop])
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 6vip is ON HOLD
+
==TUDOR DOMAIN OF TUMOR SUPPRESSOR P53BP1 WITH MFP-6008==
-
 
+
<StructureSection load='6vip' size='340' side='right'caption='[[6vip]], [[Resolution|resolution]] 1.36&Aring;' scene=''>
-
Authors: The, J., Hong, Z., Dong, A., Headey, S., Gunzburg, M., Doak, B., James, L.I., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Brown, P.J., Structural Genomics Consortium (SGC)
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[6vip]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VIP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6VIP FirstGlance]. <br>
-
Description: TUDOR DOMAIN OF TUMOR SUPPRESSOR P53BP1 WITH MFP-6008
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=QXY:{4-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]phenyl}(4-ethylpiperazin-1-yl)methanone'>QXY</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6vip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vip OCA], [http://pdbe.org/6vip PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6vip RCSB], [http://www.ebi.ac.uk/pdbsum/6vip PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6vip ProSAT]</span></td></tr>
 +
</table>
 +
== Disease ==
 +
[[http://www.uniprot.org/uniprot/TP53B_HUMAN TP53B_HUMAN]] Note=A chromosomal aberration involving TP53BP1 is found in a form of myeloproliferative disorder chronic with eosinophilia. Translocation t(5;15)(q33;q22) with PDGFRB creating a TP53BP1-PDGFRB fusion protein.
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/TP53B_HUMAN TP53B_HUMAN]] Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.<ref>PMID:12364621</ref> <ref>PMID:17190600</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Arrowsmith, C H]]
 +
[[Category: Bountra, C]]
 +
[[Category: Brown, P J]]
 +
[[Category: Doak, B]]
 +
[[Category: Dong, A]]
 +
[[Category: Edwards, A M]]
[[Category: Gunzburg, M]]
[[Category: Gunzburg, M]]
-
[[Category: James, L.I]]
 
-
[[Category: Arrowsmith, C.H]]
 
-
[[Category: Dong, A]]
 
-
[[Category: Brown, P.J]]
 
-
[[Category: Edwards, A.M]]
 
[[Category: Headey, S]]
[[Category: Headey, S]]
[[Category: Hong, Z]]
[[Category: Hong, Z]]
 +
[[Category: James, L I]]
 +
[[Category: Structural genomic]]
[[Category: The, J]]
[[Category: The, J]]
-
[[Category: Structural Genomics Consortium (Sgc)]]
+
[[Category: Mfp-6008]]
-
[[Category: Doak, B]]
+
[[Category: Protein binding]]
-
[[Category: Bountra, C]]
+
[[Category: Sgc]]
 +
[[Category: Transcription]]
 +
[[Category: Tudor]]

Revision as of 04:31, 13 February 2020

TUDOR DOMAIN OF TUMOR SUPPRESSOR P53BP1 WITH MFP-6008

PDB ID 6vip

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6vip"
Personal tools