This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
TGF-beta receptor
From Proteopedia
(Difference between revisions)
| Line 19: | Line 19: | ||
</StructureSection> | </StructureSection> | ||
| - | == 3D Structures of TGF-β receptor== | ||
| - | |||
| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | |||
| - | * TGF-β receptor I; Domains: extracellular 33-112; kinase 200-503 | ||
| - | |||
| - | **[[1ias]], [[5e8s]] – hTGFBR-I kinase domain – human <br /> | ||
| - | **[[5e8t]], [[5e8u]] – hTGFBR-I kinase domain (mutant) <br /> | ||
| - | **[[5e8w]], [[5e8x]] – hTGFBR-I kinase domain (mutant) + staurosporine<br /> | ||
| - | **[[2l5s]] – hTGFBR-I extracellular domain - NMR<br /> | ||
| - | **[[1b6c]] – hTGFBR-I kinase domain + FKBP12 <br /> | ||
| - | **[[1py5]], [[3faa]], [[3gxl]], [[3hmm]], [[2wot]], [[2wou]], [[3kcf]], [[2x7o]], [[3tzm]], [[4x0m]], [[4x2j]], [[4x2k]], [[4x2n]], [[5qim]], [[5fri]], [[4x2g]], [[4x2f]] – hTGFBR-I kinase domain + inhibitor <br /> | ||
| - | **[[5e8z]], [[5qik]], [[5qil]], [[5qtz]], [[5qu0]], [[6b8y]], [[5e90]] – hTGFBR-I kinase domain (mutant) + inhibitor<br /> | ||
| - | **[[1vjy]] – hTGFBR-I residues 1-303 + inhibitor <br /> | ||
| - | **[[5usq]] – hTGFBR-I residues 123-421 + inhibitor <br /> | ||
| - | **[[1rw8]] – hTGFBR-I truncated kinase domain + inhibitor <br /> | ||
| - | **[[6mac]] – hTGFBR-I extracellular domain + GDF-11 + activin receptor 2B- <br /> | ||
| - | |||
| - | * TGF-β receptor II | ||
| - | |||
| - | **[[1m9z]] – hTGFBR-II extracellular domain <br /> | ||
| - | **[[1plo]], [[4p7u]] – hTGFBR-II extracellular domain (mutant) - NMR<br /> | ||
| - | **[[4xjj]] – hTGFBR-II extracellular domain (mutant) + inhibitor<br /> | ||
| - | **[[5e8v]] – hTGFBR-II kinase domain (mutant) <br /> | ||
| - | **[[5e8y]] – hTGFBR-II kinase domain (mutant) + staurosporine<br /> | ||
| - | **[[5e92]] – hTGFBR-II kinase domain (mutant) + AMPPNP<br /> | ||
| - | **[[5qin]], [[5e91]] – hTGFBR-II kinase domain + inhibitor <br /> | ||
| - | **[[1ktz]] – hTGFBR-II extracellular domain + TGF-β3 <br /> | ||
| - | **[[5ty4]] – hTGFBR-II extracellular domain + mmTGF-β2 <br /> | ||
| - | **[[5tx4]] – mTGFBR-II extracellular domain (mutant) + hTGF-β2 - mouse<br /> | ||
| - | **[[1ks6]] – cTGFBR-II extracellular domain - chicken<br /> | ||
| - | |||
| - | * TGF-β receptor III | ||
| - | |||
| - | **[[3qw9]] – TGFBR-III ZP-C domain - rat<br /> | ||
| - | **[[4ajv]] – mTGFBR-III ZP-C domain <br /> | ||
| - | |||
| - | * TGF-β receptor I+II | ||
| - | |||
| - | **[[2pjy]] – hTGFBR-I extracellular domain (mutant) + hTGFBR-II extracellular domain (mutant) + TGF-β3 <br /> | ||
| - | **[[3kfd]] – hTGFBR-I extracellular domain + hTGFBR-II extracellular domain + TGF-β1 <br /> | ||
| - | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 11:21, 16 February 2020
| |||||||||||
References
- ↑ Wrana JL. TGF-beta receptors and signalling mechanisms. Miner Electrolyte Metab. 1998;24(2-3):120-30. PMID:9525694
- ↑ Frischmeyer-Guerrerio PA, Guerrerio AL, Oswald G, Chichester K, Myers L, Halushka MK, Oliva-Hemker M, Wood RA, Dietz HC. TGFbeta receptor mutations impose a strong predisposition for human allergic disease. Sci Transl Med. 2013 Jul 24;5(195):195ra94. doi: 10.1126/scitranslmed.3006448. PMID:23884466 doi:http://dx.doi.org/10.1126/scitranslmed.3006448
