6puj
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of human MAIT A-F7 TCR in complex with human MR1-3`OH-Propyl-5-OP-U== | |
| - | + | <StructureSection load='6puj' size='340' side='right'caption='[[6puj]], [[Resolution|resolution]] 1.92Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6puj]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PUJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PUJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=Q7S:6-[(3-hydroxypropyl)amino]-5-[(E)-(2-oxopropylidene)amino]pyrimidine-2,4(1H,3H)-dione'>Q7S</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6puj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6puj OCA], [http://pdbe.org/6puj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6puj RCSB], [http://www.ebi.ac.uk/pdbsum/6puj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6puj ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HMR1_HUMAN HMR1_HUMAN]] Has antigen presentation function. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT cells are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.<ref>PMID:12794138</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Awad, W]] | ||
| + | [[Category: Keller, A N]] | ||
| + | [[Category: Rossjohn, J]] | ||
| + | [[Category: Immune system]] | ||
| + | [[Category: Mait]] | ||
| + | [[Category: Metablite presentation]] | ||
| + | [[Category: Mr1]] | ||
Revision as of 06:27, 19 February 2020
Structure of human MAIT A-F7 TCR in complex with human MR1-3`OH-Propyl-5-OP-U
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