This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6qoo
From Proteopedia
(Difference between revisions)
m (Protected "6qoo" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with Fragment 18 (Isoxazole-5-carbothioamide)== | |
| - | + | <StructureSection load='6qoo' size='340' side='right'caption='[[6qoo]], [[Resolution|resolution]] 1.94Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6qoo]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QOO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QOO FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=JAB:1,2-oxazole-5-carbothioamide'>JAB</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6nvr|6nvr]]</td></tr> |
| - | [[Category: Blundell, T | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qoo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qoo OCA], [http://pdbe.org/6qoo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qoo RCSB], [http://www.ebi.ac.uk/pdbsum/6qoo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qoo ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/B1MDI3_MYCA9 B1MDI3_MYCA9]] Specifically methylates guanosine-37 in various tRNAs.[HAMAP-Rule:MF_00605][RuleBase:RU003464][SAAS:SAAS00040552] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Abell, C]] | ||
| + | [[Category: Blundell, T L]] | ||
| + | [[Category: Coyne, A G]] | ||
[[Category: Mendes, V]] | [[Category: Mendes, V]] | ||
| - | [[Category: Thomas, S | + | [[Category: Thomas, S E]] |
| - | [[Category: | + | [[Category: Whitehouse, A J]] |
| - | [[Category: | + | [[Category: Spout methyltransferase]] |
| - | [[Category: | + | [[Category: Transferase]] |
| + | [[Category: Trmd]] | ||
| + | [[Category: Trna methyltransferase]] | ||
Revision as of 09:21, 26 February 2020
Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with Fragment 18 (Isoxazole-5-carbothioamide)
| |||||||||||
